CURRICULUM VITAE
James C. Parker
PERSONAL INFORMATION:
Current
Position Title: Professor
Professional
Address: University
of South Alabama
College
of Medicine
Department
of Physiology
MSB
3024
Mobile,
Alabama 36688
Citizenship: United
States
EDUCATION:
High School Education:
Metairie
County Day School, Metairie, Louisiana -1957.
Undergraduate Education:
B.S.
- Biology & Chemistry - Washington and Lee University, Lexington, VA -
1961.
Graduate Education:
Doctorate:
Ph.D. - Physiology - University of Mississippi, Graduate School of
Medical
Sciences, Jackson, Mississippi - 1972.
Honorary Awards:
Dean's
List; Honor Roll - Washington and Lee University.
Pharmacia
Travel Award of the Microcirculatory Society, 1981 - Funds for travel to
European
Research Laboratories.
Fellowship Awards:
Mississippi
Heart Association Research Fellowship, 1973-74.
NIH
Predoctoral Fellowship, Cardiovascular Physiology, University of Mississippi
Medical
Center, 1968-72.
Mayo
Research Foundation Fellowship, June-August 1963, Experimental Pathology.
PROFESSIONAL QUALIFICATIONS:
National
Committees and Offices:
NIH
CVA-AHR Cardiovascular and Pulmonary Study Section, Washington, D.C.,
February
13-15, 1979.
Awards
Committee, United States Microcirculatory Society, 1981-84, Chairman, 1983-84.
Research
Advisory Committee, Alabama Heart Association, 1983-86.
NIH
HLI Respiratory and Applied Physiology Study Section, Washington, D.C.,
1984
- 1987.
Editorial
Board, J. Appl. Physiol., 1984-93.
Reviewer;
American Journal of Respiratory and Critical Care Medicine,
Circulation
Research, Microvascular Research, American
Journal of Physiology,
Journal
of Applied. Physiology, Journal of
Physiology (Lond.),
Journal
of Clinical Investigation, Critical Care Medicine
NIH
Trauma and Burn Research Fellowship Review Committee, 1984.
NIH
NIGMS Site Visit Committee, 1986, 1987.
NIH
Program Project Review Site Visit, Seattle, WA, 1987.
NIH
Cancer Therapeutics Review Committee Site Visit, Richmond, VA., 1987.
NIH
ARDS SCOR Review Committee Site Visit, Seattle, WA, 1988.
NIH
NLS Review Committee Site Visit, San Francisco, CA, 1987.
NIH
Physiologic Sciences Study Section, Bethesda, MD March 1-3, 1995.
NIH
SBIR/STTR Study Section, Bethesda, MD 1999.
NIH
SBIR Study Section SSS-3, Chevy Chase, MD, Feb. 27-28, 2002
Am.
Heart Assoc. S. E. Region Peer Review Committee, Tampa, FL, April 7-9, 2002
NIH
NHLBI Program Project Review Committee, Bethesda, MD, May 8, 2002
NIH
Neuro SBIR ZRG1 BSCT 10 B study section, Bethesda, MD, Dec. 4, 2003
Gulf
Coast Physiologic Society. Treasurer. 2003-4.
NIH
NIGMS Trauma, burn and perioperative injury center study section. March 9-10,
2004
Professional Society Memberships:
American
Physiological Society
Circulation
and Respiratory Sections of American Physiological Society
Microcirculatory
Society
Sigma
Xi
Lung
Water Club
International
Lymphology Society
Alabama
Heart Association
American
Heart Association, Circulation Council
North
American Vascular Biology Organization
New
York Academy of Sciences
American
Thoracic Society
Past Professional Experience:
Associate
Professor, 1980-83, University of South Alabama, College of Medicine,
Department of Physiology,
Mobile, Alabama.
Assistant
Professor, 1977-80, University of South Alabama, College of Medicine,
Department
of Physiology, Mobile, Alabama.
Assistant
Professor, 1973-77, University of Mississippi Medical Center,
Department
of Physiology, Jackson, Mississippi.
Research
Associate, 1972-73, University of Mississippi Medical Center,
Department
of Physiology and Biophysics, Jackson, Mississippi.
ACADEMIC QUALIFICATIONS:
Present Appointment:
1983-Present
- Professor, Department of Physiology
Faculty Teaching Assignments:
Pulmonary
Physiology:
1979-Pres.-
COM I Medical Physiology course
1980-
Senior elective in Physiology
1985-Pres.-
Advanced Respiratory Physiology
1981-Pres.
- Advanced Cardiovascular Physiology
1984-
Pres. BEAR Physiology course for minority students.
1990-Pres.-Journal
Club
Hematology:
1978 - COM I Medical Physiology course
Student Laboratories:
1978-Pres.-
COM I Medical Physiology
1985-Pres.Intro.
to Laboratory Physiology
Committee Assignments:
USAMC
Research Advisory Committee, 1979-83
Graduate
Student Promotions Committee, 1982-85
USAMC
Medical School Admissions Committee, 1980-84, 1992-94 Ad Hoc
American
Heart Association, Alabama Afficliate Research Advisory Committee, 1982-86
North
American Microcirculatory Society Awards Committee, 1981-84; Chairman 1983-84
USAMC
Animal Health and Welfare Committee, 1984-87
USAMC
Radiation Safety Committee, 1984-87, 1996-1999
USAMC
Medical Student Summer Research Committee, 1983-87, Chairman, 1985-86
USAMC
Continuing Education Committee 1990-1991
USAMC
Committee on Ethics in Research 1991-1992
USAMC
Patent Committee 1993-1995, Chairman, 2003-5
USAMC
Faculty Committee on Appointments, Promotions, and Evaluations 1993-1995
USAMC
Biomedical Library Committee 1993-1995
USAMC
University Faculty Grievence Committee 1994-1997
USAMC
Curriculum Committee 1995-1998
Alabama
Regional Science Fair Judge 1992-1999
USAMC
Graduate recruiting committee 2003-4
Research Grants:
As
Principal Investigator:
NIH 2 R42
HL57040 - 02 Phase II STTR,“Airway perfusion
assisted liquid ventilator”, 7/1/01-6/31/03, $500,000, J.C. Parker, P.I.,
$250,000 annual
NIH 1 P01
HL66299 Project 2, J. C. Parker, P.I.., $220,000 annual, In: “Lung endothelial
cell phenotypes”, 12/01/01-11/31/06, $6,941,491, Troy Stevens, P.I.
NIH
1 R01 HL66347 “Mechanical Injury to Lung Endothelium,” 12/1/2000
-11/31/2005,
$1,244,615, J.C. Parker, P.I., $248,923 annual.
NIH
1 R41 HL57040-01A1 STTR, “Airway perfusion assisted liquid ventilator,”
2/1/99-1/30/00,
$105,000, J.C. Parker, P.I.
American
Heart Association, Southeast Affiliate, 98101 80SE,"Mechanical ventilation
induced lung injury,"7/1/98-
6/30/00, $70,000,
J.C.Parker,P.I. American Heart
Association, #94013094, "Heterogeneity of
pulmonary blood flow and injury".
7/1/94-6/30/97, $136,000, J.C.Parker, P.I.
American
Heart Association, #91011060, "Eosinophil and neutrophil effects
on
microvascular permeability in the lung,"7/1/91-6/30/94,$74,272,
J.C.Parker,
P.I.
American
Heart Association, Alabama Affiliate, AL-G-920030,"Tracheal blood
flow
during high frequency Jet Ventilation,"7/1/92-6/30/93,
$25,000,
J.C.Parker,P.I.
NIH
1 RO1 HL37341, "Lung Microvascular Injury due to Airway Pressure",
4/1/87-3/31/90,
$197,271
NIH
2 RO1 HL24571, "Interstitial Fluid Pressure and Excluded Volume in the
Lung";
8/1/79-7/31/82, $186,268; Renewal 8/1/82-7/31/87, $316,000;
Renewal
8/1/87-7/31/92, $526,000; J.C. Parker
P.I.
American
Lung Association, "Interstitial Pressure and Excluded Volume in
the
Lung", 6/1/79-5/30/81, $25,666.
American Heart Association,
"Interstitial Pressure and Excluded Volume in
the
Lung", 7/1/79-6/30/82, $61,820.
Intramural
- University of South Alabama, 2/15/78-2/15/79, "Pulmonary Capillary
and
Interstitial Protein Transport", $5,000.
Mississippi
Heart Association, "Dynamics of Pulmonary Vascular and Extravascular
Forces", 6/1/77-5/31/79,
$18,974 (not transferred).
Mississippi
Heart Association, "Energy Metabolism in
the
Ischemic Myocardium", 6/1/75-5/31/77, $16,780.
As
Co-Investigator:
NIH R01
HL67461-01.,”Tlymphocyte role in lung ischemia - reperfusion injury.”,
4/1/01-2/28/05, $200,000/yr., (A. E. Taylor, P.I.; J.C. Parker, 20% effort).
NIH R01
HL63302-01A2 “Airway submucosal glands and cystic fibrosis disease”
4/1/01-3/31/06, $1,486,263 (Stephen T. Ballard, P.I.; J.C. Parker, 5% effort)
NIH 1 P01
HL66299 Project 2, J. C. Parker, P.I.., $220,000 annual, In: “Lung endothelial
cell phenotypes”, 12/01/01-11/31/06, $6,941,491, Troy Stevens, P.I.
American
Lung Association, "Diaphragmatic function during
mechanical
ventilation in ewes.", $50,000 (Max Ferrigno,
P.I.,
7/1/95-6/30/97; J.C. Parker, 15%).
American
Heart Association, Alabama Affiliate, "Nitric Oxide
Modulation
of Oleic Acid Injured Lungs,"7/1/95-6/30/97,
$55,450,
(Michael M. Zayek, P.I; J.C.Parker, 10% effort. NIH, "Transport Across
Alveolar
Capillary
Membrane", 9/1/77-8/31/82, $200,715;
renewal
9/1/81-8/31/87, $545,000 (A.E. Taylor, P.I.).
(Renewal
9/1/87-8/31/92,
$640,000; J.C. Parker, 15%).
Parker
B. Francis Foundation Fellowship, 9/1/78-8/31/81, $72,000; renewal
9/1/81-8/31/83,
$72,000 (A.E. Taylor, P.I.).
American
Lung Association, "Barotrauma and Microvascular Injury in the
Immature
Lung", $35,000 (Alicia Moise,P.I., 7/1/88-6/30/90;
J.C.
Parker, 15%).
Patents Awarded: U. S. Patent No. 5,706,830
awarded on Jan. 13, 1998, entitled “Liquid ventilator
and use thereof ”, to J.C. Parker, ref. No.
87647.97R243.
Ph.D
Dissertation Committees
Michelle Lynn Perry 1988
William
Keith Adkins 1991
Peter S. Wilson 1993
Laura Trout 2001
Judy
Creighton
Donna
Cioffi
Diego
Alverez
Sarah
Sayner
Brad
Swiger
Post-Doctoral
Students
Roger
M. Pitt M.D.
Lucretia
A. Hernandez M.D., Ph.D.
Toshishiga
Shibamoto M.D., Ph.D.
Keisaku
Fujimoto M.D.,Ph.D.
Sawako
Yoshikawa M.D.,Ph.D.
Mircea
Anghelescu M.D.
Siobhan
Tarpey Ph.D.
Tokashige
Miyahara M.D., Ph.D.
Medical
Student Honors Program
Jarrod
Adkison B.Ch.E.
PUBLICATIONS:
TEXTBOOKS:
1. Taylor,
A.E., K. Rehder, R. Hyatt, and J.C. Parker.
Clinical Pulmonary Physiology, Saunders Publishing Co: Philadelphia, PA,
1989.
SCIENTIFIC PAPERS AND CHAPTERS:
1. Jones,
C.E., J.C. Parker, and E.E. Smith.
Determination of myocardial acid soluble adenine nucleotides on anion
exchange thin layers. J. Chromatography 64:378-344, 1972.
2. Parker,
J.C., and E.E. Smith. Effects of
xanthine oxidase inhibition in cardiac arrest.
Surgery 71:339-344, 1972.
3. Parker,
J.C., C.E. Jones, and E.E. Smith.
Determination of acid soluble nucleosides and bases in myocardium by
thin layer methods. J.
Chromatography 79:360-363, 1973.
4. Guyton,
A.C., A.E. Taylor, R.E. Drake, and J.C. Parker. Dynamics of subatmospheric pressure in pulmonary interstitial
fluid.
In: Lung Liquids, a CIBA Foundation Symposium. Elsevier, Amsterdam, 1976.
5. Parker,
J.C., C.E. Jones, and J.X. Thomas, Jr.
Effect of ischemia and infarction on regional content of adenine
nucleotides and derivatives in canine left ventricle. Cardiology 61:279-288, 1976.
6. Parker,
J.C., E.E. Smith, and C.E. Jones. The
role of nucleoside and nucleobase metabolism in myocardial adenine nucleotide
regeneration after cardiac arrest. Circulatory
Shock 3(1):11-20, 1976.
7. Jones,
C.E., J.X. Thomas, J.C. Parker, and R.E. Parker. Acute changes in adenine nucleotides, nucleotide derivaties and
contractile force in ischemic and non-ischemic and canine myocardium following
coronary occlusion. Cardiovascular
Research 10:275-282, 1976.
8. Parker,
J.C., and D.H. Pearce. Computation of
indicator dilution flows and transit times with a pocket calculator. Am. Heart J. 91:826-827, 1976.
9. Parker,
J.C., C.E. Jones, J.X. Thomas, and H.J. Granger. A dynamic analysis of energy and contractility transients in
ischemic myocardium. Proceedings of
Summer Computer Simulation Conference, pp. 539-544, 1977.
10. Parker,
J.C., A.C. Guyton, and A.E. Taylor.
Pulmonary transcapillary exchange and pulmonary edema. In: A.C. Guyton (ed.) International
Review of Physiology, Cardiovascular Physiology III. University Park Press, Baltimore, 1978.
11. Parker,
J.C., A.C. Guyton, and A.E. Taylor.
Pulmonary interstitial and capillary pressures estimated from
intra-alveolar fluid pressures. J. Appl. Physiology 44:267-276, 1978.
12. Guyton,
A.C., J.C. Parker, A.E. Taylor, T.E. Jackson, and D.S. Moffatt. Forces governing water movement in the
lung. In: Pulmonary edema. A.P. Fishman and E.M. Renkin, eds., Am.
Physiological Society, Bethesda, MD, 1979.
13. Parker,
J.C., and A.E. Taylor. Pulmonary
interstitial and capillary pressures estimated from intra-alveolar fluid
pressures (Letter), J. Appl. Physiol. 47-643-644, 1979.
14. Parker,
J.C., A.E. Taylor, R.E. Parker, and D.N. Granger. Vertical gradient in regional vascular resistance and pre- to
post-capillary resistance ratios in the dog lung. Lymphology 12:191-200, 1979.
15. Parker,
J.C., J.H. Falgout, R.E. Parker, D.N. Granger, and A.E. Taylor. The effect of volume loading on interstitial
albumin exclusion and lymph flow in the lung.
Circ. Res. 45:440-450, 1979.
16. Granger,
D.N., T. Miller, R.E. Allen, R.E. Parker, J.C. Parker, and A.E. Taylor. Permselectivity of the cat blood-lymph
barrier to endogenous macromolecules. Gastroenterology
77:103-109, 1979.
17. Granger,
D.N., N.A. Mortillaro, P.R. Kvietys, G. Rutili, J.C. Parker, and A.E.
Taylor. Role of the interstitial matrix
during intestinal volume absorption. Am.
J. Physiol. 238:G183-G189, 1980.
18. Parker,
J.C., R.E. Parker, D.N. Granger, and A.E. Taylor. Vascular permeability and transvascular fluid and proteins
transport in the dog lung. Circ. Res.
48:549-561, 1981.
19. Parker,
J.C., H.J. Falgout, F.A. Grimbert, and A.E. Taylor. The effect of increased vascular pressure on albumin excluded
volume and lymph flow in the dog lymph.
Circ. Res. 47:866-875, 1980.
20. Taylor,
A.E., J.C. Parker, D.N. Granger, and G. Rutili. Pulmonary edema: Changes in Starling Forces and Lymph Flow. In: Tissue Fluid Pressure and Composition. (Ed.) Alan Hargens, Williams and Wilkins
Co., pp. 135-143, 1981.
21. Perry,
M.A., and J.C. Parker. Indicator
measurement of splanchnic blood flow.
In: Measurement of Blood Flow.
(Eds.) D.N. Granger and G.B. Bulkley, Williams and Wilkins Co., pp.
159-176, 1981.
22. Parker,
J.C., F. Grimbert, G. Rutili, and A.E. Taylor.
Pulmonary lymph plasma oncotic pressure gradients after hemodilution,
increased vascular pressures, and albumin infusion. In: Recent Advances in Microcirculatory Research (Ed.) P.
Gaethtgens, S. Karger, Basel, pp. 251-254, 1981.
23. Taylor,
A.E., J.C. Parker, D.N. Granger, N.A. Motrillaro, and G.Rutili. Assessment of capillary permeability using
lymphatic protein flux: Estimation of the osmotic reflection coefficient. In: The Microcirculation, (Ed.) R. Effros,
H. Schmid-Schonbein, and J. Ditzel, Academic Press, pp. 19-32, 1981.
24. Parker,
J.C., R.C. Allison, and A.E. Taylor.
Edema affects intralveolar fluid pressures and interdependence in dog
lungs. J. Appl. Physiol.
51:911-921, 1981.
25. Grimbert,
F.A., J.C. Parker, and A.E. Taylor.
Increased pulmonary vascular permeability following acid aspiration. J.
Appl. Physiol. 51:335-345, 1981.
26. Kinnebrew,
P.S., J.C. Parker, J.J. Falgout, and A.E. Taylor. Pulmonary microvascular permeability following E. coli
endotoxin and hemorrhage. J. Appl.
Physiol. 52:403-409, 1982.
27. Rutili,
G., P. Kvietys, J.C. Parker, and A.E. Taylor.
Increased microvascular permeability induced by ANTU. J. Appl. Physiol. 52:1316-1323, 1982.
28. Rutili,
G., D.N. Granger, A.E. Taylor, J.C. Parker, and N.A. Mortillaro. Analysis of lymphatic protein data IV. Comparison of the different methods used to
estimate reflection coefficients and permeability-surface area products. Microvasc. Res. 23:347-360, 1982.
29. Parker,
J.C., M. Crain, F. Grimbert, G. Rutili, and A.E. Taylor. Total lung lymph flow and fluid
compartmentation in edematous dog lungs.
J. Appl. Physiol. 51:1268-1277, 1981.
30. Taylor,
A.E., J.C. Parker, P.R. Kvietys, and M. Perry.
Pulmonary interstitium in capillary exchange. In: Mechanisms of Lung Microvascular Injury. (Ed.) N.C. Staub and A. Malik, N.Y. Acad.
Sci. 384:146-165, 1982.
31. Taylor,
A.E., J.C. Parker, and R.C. Allison.
Capillary exchange of fluid and protein. In: Critical Care Vol. 3.
(Ed.) W.C. Shoemaker and W.L. Thompson.
Soc. Crit. Care, Fullerton, CA, pp. III B 1-26, 1982.
32. Parker,
J.C., and A.E. Taylor. Comparison of
capsular and intra-alveolar fluid pressures in the lung. J. Appl. Physiol. 52:1444-1454, 1982.
33. Martin,
D.J., J.C. Parker, and A.E. Taylor.
Simultaneous comparison of tracheobronchial and right duct lymph
dynamics in dogs. J. Appl. Physiol. 54:199-207, 1983.
34. Holloway,
H.M. Perry, J. Downey, J.C. Parker, and A.E. Taylor. Estimation of effective capillary pressure in intact lungs. J. Appl. Physiol. 54:846-851, 1983.
35. Parker,
J.C., D. Martin, and A.E. Taylor.
Extravascular fluid compartmentation and lymph flow in edematous
lungs. In: Advances in Lympholosy. (Ed.) V. Bartos and J.W. Davidson,
Avicenum, Czech., Medical Press, Prague, pp.
192-202, 1982.
36. Parker,
J.C., P.R. Kvietys, K.P. Ryan, and A.E. Taylor. Comparison of isogravimetric and venous occlusion pressures in
isolated dog. J. Appl. Physiol.
55:964-968, 1983.
37. Parker,
J.C., L. Campbell, S. Gilchrist, G. Longenecker, and A.E. Taylor. Failure of myocardial ischemia to increase
pulmonary microvascular permeability in dogs.
J. Appl. Physiol. 56:691-699, 1984.
38. Taylor,
A.E., D. Martin, and J.C. Parker. The
effects of oxygen radicals on pulmonary edema formation. Surgery 94:433-438, 1983.
39. Parker,
J.C., D. Martin, G. Rutili, and A.E. Taylor.
Prevention of Free Radical Mediated Vascular Permeability Increases in
Lung Using Superoxide Dismutase. Chest
83:52S-54S, 1983.
40. Rutili,
G., J.C. Parker, and A.E. Taylor. Fluid
balance in ANTU-injured lungs during crystalloid and colloid infusions. J. Appl. Physiol. 56:983-998, 1984.
41. Perry,
M.A., C.A. Navia, D.N. Granger, J.C. Parker, and A.E. Taylor. Calculation of equivalent pore radii in dog
hind paw capillaries using endogenous lymph and plasma proteins. Microvasc. Res. 26:250-253, 1983.
42. Allison,
R.C., J.C. Parker, C.E. Duncan, and A.E. Taylor. Effect of air embolism on the measurement of extravascular lung
thermal volume. J. Appl. Physiol.:
Respirat. Environ. Exercise Physiol. 54(4):943-949, 1983.
43. Martin,
D., K. Rehder, J.C. Parker, and A.E. Taylor.
High-frequency ventilation: lymph protein flux, and lung water. J. Appl. Physiol.: Respirat. Environ.
Exercise Physiol. 57(1):240-245, 1984.
44. Rippe,
B., R.C. Allison, J.C. Parker, and A.E. Taylor. Effects of histamine serotonin, and norepinephrine on circulation
of dog lungs. J. Appl. Physiol.:
Respirat. Environ. Exercise Physiol. 57(1):223-232, 1984.
45. Rippe,
B., M. Townsley, J. Thigpen, J.C. Parker, R.J. Korthuis, and A.E. Taylor. Effects of vascular pressure on the
pulmonary microvasculature in isolated dog lungs. J. Appl. Physiol.: Respirat. Environ. Exercise Physiol.
57(1):233-239, 1984.
46. Parker,
J.C., M.A. Perry, and A.E. Taylor.
Permeability of the microvascular barrier. In: Edema. Eds.
N.C. Staub and A.E. Taylor. Chap.
7. Raven Press, New York, 1984, pp.
143-187.
47. Parker,
J.C., J. Ryan, and A.E. Taylor. Plasma-lymph
albumin kinetics, total lymph flow and tissue hematocrit in normally hydrated
dog lungs. Microvasc. Res.
28:254-269, 1984.
48. Parker,
J.C., M.I. Townsley, B. Rippe, and J. Thigpen.
Increased microvascular permeability in dog lungs due to high peak
airway pressures. J. Appl. Physiol.
57:1809-1816, 1984.
49. Taylor,
A.E., B. Rippe, M. Townsley, R. Korthuis, and J.C. Parker. Interstitial lung tissue fluid
resistance. In: Frontiers in
Physiology Research, ed., by D.G. Garlick and P.I. Korner. Australian Academy of Science, pp. 120-161,
1984.
50. Gilchrist,
S.A., and J.C. Parker. Exclusion of
charged macromolecules in the pulmonary interstitium. Microvasc. Res. 30:88-98, 1985.
51. Taylor,
A.E., and J.C. Parker. The interstitial
spaces in lymph flow. In: Handbook
of Physiology: Respiration, Vol. 4, A.P. Fishman and A.B. Fisher (eds.),
Am. Physiol. Soc., Bethesda, MD 1985, pp. 167-320.
52. Rippe,
B., M. Townsley, J.C. Parker, and A.E. Taylor.
The osmotic reflection coefficient for total plasma protein in lung
microvessels. J. Appl. Physiol.
58:436-442, 1985.
53. Parker,
J.C., S. Gilchrist, and A.E. Taylor.
Plasma-lymph exchange and interstitial distribution volumes of charged
macromolecules. J. Appl. Physiol.
59:1128-1136, 1985.
54. Parker,
J.C., B. Rippe, and A.E. Taylor. Fluid
filtration and protein clearances through large and small pore populations in
dog lung capillaries. Microvas. Res.
31:1-17, 1986.
55. Parker,
J.C. Transvascular clearance and distribution
of charged macromolecules in ANTU lung injury.
J. Appl. Physiol. 60:1221-1229, 1986.
56. Taylor,
A.E., J.C. Parker, and B. Rippe. Edema
and the tissue resistance safety factor.
Chapter 9. In: Tissue
Nutrition and Viability, Ed. by A.R. Hargens. Springer-Verlag, New York, NY, 1986. pp. 185-196.
57. Rippe,
B., J.C. Parker, M.I. Townsley, N.A. Mortillaro, and A.E. Taylor. Segmental vascular resistances and
compliances in dog lung. J. Appl.
Physiol. 62:1206-1215, 1987.
58. Parker,
J.C., M. Miniati, R. Pitt, and A.E. Taylor.
Interstitial distribution of charged macromolecules in the dog lung: A
kinetic model. Ann. Biomed. Eng.
15:157-172, 1987.
59. Townsley,
M.I., R.J. Korthuis, B. Rippe, J.C. Parker, and A.E. Taylor. Validation of double vascular occlusion
method for Pc,i in lung and skeletal muscle.
J. Appl. Physiol. 61:127-132, 1986.
60. Pitt,
R.M., J.C. Parker, G.J. Jurkovich, A.E. Taylor, and P.W. Curreri. Analysis of altered capillary pressure and
permeability after thermal injury. J.
Surg. Res. 42:693-702, 1987.
61. Townsley,
M.I., J.C. Parker, R.J. Korthuis, and A.E. Taylor. Alterations in hemodynamics and Kf,c during lung mass
resection. J. Appl. Physiol.
63:2460-2466, 1987.
62. Parker,
J.C. Transport and distribution of charged macromolecules in lungs. Adv.
Microcirc. 13:150-159, 1987.
63. Miniati,
M., J.C. Parker, M. Pistolesi, J. Cartledge, C. Giuntini, and A.E. Taylor. Albumin reabsorption kinetics from the
pleural spaces of dogs. Am. J.
Physiol. 255:H375-H385, 1988.
64. Parker,
J.C. Transvascular transport and distribution volumes of charged macromolecules
in normal and injured lungs. In: Interstitial
Fluid Dynamics, ed. by N.C. Staub and A. Hargens. S. Karger, Basel, 1988.
65. Parker,
J.C., M. Miniati, A.E. Taylor, and R. Pitt.
Pulmonary microvascular permeability of charged isozymes of lactate
dehydrogenase (LDH) in isolated dog lungs.
In: M. Tsuchiya (Ed.) Microcirculation - An Update, Vol. 1
(1987).
66. Taylor,
A.E., J.C. Parker, R.C. Allison, and M. Perry.
Capillary exchange of fluid and protein. In: Textbook of Critical Care, ed. by W. Shoemaker, W.L.
Thompson, and P.R. Holbrook. Saunders
Publishing Co: Philadelphia, PA, 1988.
67. Grimbert,
F.A., D. Martin, J.C. Parker, and A.E. Taylor.
Pulmonary blood flow vs. microvascular pressure effects on lung lymph
flow in dogs. Am. J. Physiol.
255:H1149-H1155, 1988.
68. Townsley,
M.I., J.C. Parker, G.L. Longenecker, M.L. Perry, R.M. Pitt, and A.E.
Taylor. Pulmonary embolism: Analysis of
endothelial pore sizes in canine lung. Am.
J. Physiol. 255:H1075-H1083, 1988.
69. Taylor,
A.E., K. Rehder, R. Hyatt, and J.C. Parker.
Clinical Pulmonary Physiology, Saunders Publishing Co: Philadelphia, PA,
1989.
70. Cope,
D.K., J.C. Parker, R.C. Allison, and A.E. Taylor. The Gaar equation is not a reliable predictor of pulmonary
capillary pressure. Critical Care
Medicine 17:300, 1989.
71. Parker,
J.C., M.I. Townsley, and J.T. Cartledge.
Edema increases transvascular filtration rate but not filtration coefficient
in dog lungs. J. Appl. Physiol.
66:1553-1560, 1989.
72. Hernandez,
L.A., K.J. Peevy, A.A. Moise, and J.C. Parker.
Chest wall restriction limits high airway pressure-induced lung injury
in young rabbits. J. Appl. Physiol.
66:2364-2368, 1989.
73. Barman,
Scott A., Jeffrey L. Ardell, J.C. Parker, Michele L. Perry, and A.E.
Taylor. Pulmonary and systemic blood
flow contributions to upper airways in canine lung. Am J. Physiol. 255 (Heart Circ. Physiol. 24): H1130-H1135,
1988.
74. Allison,
Ronald C., Bengt Rippe, V. Ravi Prasad, J.C. Parker, and A.E. Taylor. Pulmonary vascular permeability and
resistance measurements in control and ANTU-injured dog lungs. Am. J. Physiol. 256 (Heart Circ.
Physiol. 25): H1711-1718, 1989.
75.
Cope, D.K., J.C. Parker, M.D. Taylor, M. Houston, and A.E. Taylor. Pulmonary capillary pressures during hypoxia
and hypoxemia: Experimental and clinical studies. Crit. Care Med. 17:853-857, 1989.
76. Peevy,
K.J., L.A. Hernandez, A.A. Moise, J.C. Parker.
Barotrauma and microvascular injury in lungs of non-adult rabbits:
Effect of ventilation pattern. Critical
Care Medicine 18:634-637, 1990.
77. Shibamoto,
T., J.C. Parker, A.E. Taylor, and M.I. Townsley. Derecruitment of filtration surface area in paraquat-injured isolated
dog lungs. J. Appl. Physiol.
68:1581-1589, 1990.
78. Shibamoto,
T., A.E. Taylor, and J.C. Parker. PO2 modulation of paraquat-induced
microvascular injury in isolated dog lungs.
J. Appl. Physiol. 68:2119-2127, 1990.
79. Parker,
J.C., L.A. Hernandez, G.L. Longenecker, K. Peevy, and W. Johnson. Lung edema due to high peak inspiration
pressures in dogs: Role of increased microvascular filtration pressure and
permeability. Am. Rev. Respir. Dis.
142:321-328, 1990.
80. Fujimoto,
K., J.C. Parker, and S.G. Kayes.
Activated eosinophils increase vascular permeability and resistance in
isolated perfused rat lungs. Am.
Rev. Respir. Dis. 142:1414-1421, 1990.
81.
Hernandez, L.A., P.J. Coker, S. May, A.L. Thompson, and J.C.
Parker. Mechanical ventilation
increases microvascular permeability in oleic acid injured lungs. J. Appl. Physiol. 69:2057-2061, 1990.
82.
Adkins, W.K., L.A. Hernandez, P.J. Coker, B. Buchanan, and J.C.
Parker. Age affects susceptibility to
pulmonary barotrauma in rabbits. Critical
Care Medicine 19:390-393, 1991.
83.
Ishibashi, M., R.K. Reed, M.I. Townsley, J.C. Parker, and A.E.
Taylor. Albumin transport across
pulmonary capillary interstitial barrier in anesthetized dogs. J. Appl. Physiol. 70(5):2104-2110,
1991.
84. Cope,
D.K., R.C. Allison, J.N. Miller, J.C. Parker, and A.E. Taylor. Estimation of pulmonary capillary pressure
in intact dog lungs using the arterial occlusion technique [letter; comment]. Am. Rev. Respir. Dis.
141(6):1602-1603, 1990.
85.
Parker, J.C., D.K. Cope, and M.P. Houston. Regional pulmonary vascular pressures and resistances during
unilateral hypoxia. [letter] Crit. Care Med. 18:1493-1494, 1990.
86.
Parker, J.C., L.A. Hernandez, and K. Peevy. What is the mechanism of pulmonary edema during high volume
ventilation? [letter, reply] Am. Rev. Respir. Dis. 143:1198-1200,
1991.
87. Fujimoto, K., J.C. Parker, and S.G.
Kayes. O2 radical scavengers
protect against eosinophil-induced injury in isolated perfused rat lungs. J.
Appl. Physiol. 73:687-694,1992.
88. Shibamoto, T. and J.C. Parker. Fructose 1,6-diphosphate augments paraquat
injury in isolated dog lungs. J.
Appl. Physiol. 71(5):1830-36, 1991.
89. Parker, J.C., L.A. Hernandez, and K.J.
Peevy. High Volume Stress Failure of Pulmonary Capillaries. In: High
Altitude Medicine. Eds. G. Ueda, J.T. Reeves, and M. Sekiguchi. Shinshu
Univ. Press, Matsumoto, Japan, pp.139-144,1992.
90. Coker, P.J., L.A. Hernandez, K.J. Peevy,
W.K. Adkins, and J.C. Parker. Increased
sensitivity to mechanical ventilation in non-compliant young rabbit lungs. Crit.
Care Med. 20:635-40,1992.
91. Shibamoto, T. and J.C.Parker. Effects of
hyperoxia, hypoxia and fructose-1,6-diphosphate on paraquat induced pulmonary
injury in isolated dog lungs. In: Pulmonary Circulation Research, Eds.
H. Nagano, T. Nakada, Y. Sagawa. Kieio Univ. Press. 1991, pp.43-50.
92. Parker, J.C., L.A. Hernandez, and K.J.
Peevy. Mechanisms of ventilator-induced lung injury. Crit. Care Med.
21:131-143, 1993.
93. Yoshikawa, S., S.G. Kayes, and J.C. Parker.
Eosinophils increase lung microvascular permeability via the
peroxidase-hydrogen peroxide-halide system. Am. Rev. Respir. Dis.
147:914-920, 1993.
94.
Parker, J.C., R. Prasad, R.C. Allison, W.V. Wojchiechowski, and S.L.
Martin. Capillary filtration
coefficient (Kf,c) using laser densitometry in isolated dog
lungs. J. Appl. Physiol.
74:1981-1987, 1993.
95. Reed, R.K., M. Ishibashi, M.I. Townsley,
J.C. Parker, and A.E. Taylor. Blood-to-lymph clearance vs. Lymph analysis in
determinating capillary transport characteristics for albumin in skin. Am. J.
Physiol. 264:H1394-401, 1993.
96. Parker, J.C. Ventilator-induced injury.
ITACCS Newsletter 4:12-14,1994.
97. Townsley, M.I., R. K. Reed, M. Ishibashi,
J.C. Parker, T.C. Laurent, and A. E. Taylor. Hyaluronan efflux from canine lung
with increased hydrostatic presssure and saline loading. Am. J. Respir. Crit
Care Med. 150:1606-11,1994.
98. Parker, J.C., J.A. Ardell, C.R. Hamm, S. A.
Barman, and P.A. Coker. Regional pulmonary blood flow during rest, tilt, and
exercise in unanesthetized dogs. J.
Appl. Physiol. 78:838-846, 1995.
99. Cavanagh,K.A., H.F. Hill, W. Wojciechowski,
and J.C. Parker. Regional tracheal blood flow during conventional and high-frequency
ventilation in sucking pigs. Crit. Care Med. 24: 280-286, 1996.
100. Yoshikawa, S., S.G. Kayes, S. L. Martin,
and J.C. Parker. Eosinophilia induced vascular and airway remodeling and
hyperresponsiveness in rat lungs. J.
Appl. Physiol. 81(3): 1279-1287, 1996.
101. Parker, J.C., C.B. Cave, J.L. Ardell, C. R.
Hamm, and S. G. Williams. Vascular tree structure affects lung blood flow
heterogeneity simulated in three dimensions. J. Appl. Physiol. 83(4):1370-82,
1997.
102. Parker, J.C., E.A. Breen, and J.B. West.
High vascular and airway pressures increase interstitial protein mRNA
expression in isolated rat lungs. J.
Appl. Physiol. 83(5):1697-1705, 1997.
103. Parker, J.C., and C. Ivey. Isoproterenol
attenulates and edema augments high
vascular pressure induced permeability increases in lung. J. Appl. Physiol. 83(6): 1962-1967, 1997.
104. 2. Anglade, D.J., M. Corboz, S. Nazir, A.
Menaquar, J.C. Parker, and F. A.
Grimbert. Blood flow vs venous pressure effects on filtration coefficient in oleic
acid injured lung. J. Appl. Physiol. 84 (3): 1011-1023, 1998.
105. Parker, J.C., C. Ivey and J. Allan Tucker.
Gadolinium prevents high airway pressure induced permeability increases in
isolated rat lungs. J. Appl. Physiol. 84(4): 1113-1118, 1998.
106. Parker, J.C., C. L. Ivey and J.A. Tucker.
Phosphotyrosine phosphatase inhibition increases airway pressure induced lung
injury. J. Appl. Physiol. 85:1753-1761, 1998.
107. Parker, J.C., M.I. Townsley, and T.
Stevens. Ca2+ dependence of mechanical injury in lung capillaries (letter). J.
Appl. Physiol. 86: 775-6, 1999.
108. Parker, J.C., and A. E. Taylor. Oxygen
toxicity. In: The lung at depth. Eds. C.E.G. Lundgren and J.N. Miller. Vol 132:
Lung biology in health and disease. Series Ed. C. Lenfant. Marcel Dekker, Inc.
New York. Pages 165-210, 1999.
109. Parker, J.C., M.N. Gillespie, A.E. Taylor,
and S. L. Martin. Capillary filtration coefficient, vascular resistance and
compliance in isolated mouse lungs. J. Appl. Physiol. 87:1421-1427, 1999.
110. Parker, J.C.. Inhibitors of myosin light
chain kinase, phosphodiesterase and calmodulin attenuate ventilator induced
lung injury. J. Appl. Physiol. 89: 2241-2248, 2000.
115. Parker, J. C. and S. Yoshikawa. Vascular segmental permeabilities at
high peak inflation pressure in isolated rat lungs. Am. J. Physiol.: Lung Cell.
Mol. Physiol. 283: L1203-L1209, 2002.
116. Taylor, A. E. and J.C. Parker. Perspectives
Review: Interstitial excluded volumes: The effect of charge. J. Physiol.
553.2:333, 2003.
117. Yoshikawa, S., J. A. King, S. D. Reynolds,
B, R. Stripp and J. C. Parker Time and Pressure Dependence of Transvascular
Clara Cell Protein, Albumin and IgG Transport during Ventilator Induced Lung
Injury in Mice. Am. J. Physiol. 286: L604-L612, 2004.
118. Parker, J.C. and M. I. Townsley. Evaluation
of Lung Injury in Rats and Mice. Invited Review. Am. J. Physiol.: Lung Cell.
Mol. Physiol. 286: L231-L246, 2004.
119. Yoshikawa, S., J. A. King, R. N. Lausch,
A. M. Penton, F.G. Eyal and J.C. Parker. Acute Ventilator Induced
Vascular Permeability and Cytokine Responses in Isolated and In Situ Mouse
lungs. J. Appl. Physiol. 97:2190-2199, 2004
PAPERS ACCEPTED, IN PRESS, AND SUBMITTED FOR
PUBLICATION:
1. Yoshikawa, S., T. Miyahara, S. D. Reynolds, B, R. Stripp, M. Anghelescu, F. G.
Eyal and J. C. Parker. Clara cell secretory protein and phospholipase A2
modulate acute ventilator induced lung injury in mice. J. Appl. Physiol. In
Press.
2. Parker, J.C., T. Miyahara, and A. Anghelescu.
Chapter 2-5. Acute passive and active changes in microvascular permeability
during lung distention. In: Ventilator induced lung injury. Eds. D. Dreyfuss,
R. Hubmayr, and G. Saumon. Vol 138: Lung biology in health and disease. Series
Ed. C. Lenfant. Marcel Dekker, Inc. New York. In Press.
ABSTRACTS:
1. Smith,
E.E., J.C. Parker, and D. Hinton.
Intestinal enteritis and fluid loss associated with hemorrhagic
shock. Fed. Proc., 1969.
2. Parker,
J.C., and E.E. Smith. Serum uric acid
levels during cardiac arrest. J.
Miss. Aca. Sci. 15, 1970.
3. Parker,
J.C., C.E. Jones, and E.E. Smith.
Determination of myocardial purines during cardiac arrest and
recovery. J. Miss. Acad. Sci.
16, 1971.
4. Parker,
J.C. and E.E. Smith. Myocardial free
energy purines during cardiac arrest and recovery. The Physiologist 14:206, 1971.
5. Parker,
J.C. and E.E. Smith. Adenosine
nucleotide substrate depletion and survival in cardiac arrest. Fed. Proc., 1972.
6. Parker,
J.C., C.E. Jones, and E.E. Smith. A
concept of adenosine nucleotide substrate washout in cardiac arrest. J. Miss. Acad. Sci. 17, 1972.
7. Ferguson,
J.D., J.C. Parker, C.E. Jones, and E.E. Smith.
Effect of allopurinol on adenine nucleotide degradation in cardiac
arrest. J. Miss. Acad. Sci. 17,
1972.
8. Parker,
J.C. Computer stimulation of adenine
nucleotide kinetics in the arrested myocardium. J. Miss. Acad. Sci. 18, 1973.
9. Parker,
J.C., and C.E. Jones. Changes in energy
conservation in ischemic and non-ischemic myocardium following coronary
occlusion. J. Miss. Acad. Sci.
18, 1973.
10. Thomas,
J.X., C.E. Jones, and J.C. Parker.
Studies of adenine nucleotides and metabolites following coronary
occlusion. Fed. Proc. 33:262,
1974.
11. Thomas,
J.X., C.E. Jones, and J.C. Parker.
Acute and chronic studies of adenine nucleotides and metabolites
following coronary occlusion. J.
Miss. Acad. Sci. 19, 1974.
12. Parker,
J.C., C.E. Jones, and J.X. Thomas, Jr.
Regional contractility studies in left ventricular following coronary
occlusion. J. Miss. Acad. Sci.,
1974.
13. Thomas,
J.X., C.E. Jones, and J.C. Parker.
Acute changes in adenine nucleotides and contractile force in ischemic
and non-ischemic myocardium following coronary occlusion. The Physiologist 17:344, 1974.
14. Parker,
J.C., C.E. Jones, and J.X. Thomas.
Inotropic effects of nucleoside infusion on ischemic and non-ischemic
myocardium. J. Miss. Acad. Sci.
20 (Suppl), 1975.
15. Parker,
J.C., A.C. Guyton, and A.E. Taylor.
Estimation of pulmonary interstitial fluid pressures. The Physiologist 19:322, 1976.
16. Parker,
J.C., A.E. Taylor, and A.C. Guyton.
Relationship of capillary, interstitial and interdependance forces in
the lung. Fed. Proc. 36:536,
1977.
17. Parker,
J.C., and A.E. Taylor. Determinants of
the vertical gradient in pulmonary extravascular fluid volume. The Physiologist 20:71, 1977.
18. Parker,
J.C., and A.E. Taylor. Vertical
distribution of pre- to post-capillary resistance ratios in the lung. Microvasc. Res., 1978.
19. Parker,
J.C., A.E. Taylor, and A.C. Guyton.
Measurement of pulmonary extravascular and vascular fluid volumes by
constant infusion of a thermal indicator.
Fed. Proc. 37:635, 1978.
20. Parker,
J.C. Physiology of pulmonary capillary
fluid exchange. Hydrostatic pressure in
the capillaries and tissues. Proc. Postgraduate Assembly, NY Soc. of Anesth.,
1978.
21. Taylor,
A.E., R.E. Parker, J.C. Parker, and D.N. Granger. Pre- and post-capillary resistances in isolated dog lungs during
alveolar hypoxia. The Physiologist
21:119, 1978.
22. Parker,
J.C., R.E. Parker, D.N. Granger, and A.E. Taylor. Vertical gradient in pulmonary interstitial fluid pressure. The Physiologist 21:89, 1978.
23. Shackleford,
J.S., D.N. Granger, A.E. Taylor, and J.C. Parker. Mechanism of PGE induced transmucosal protein efflux in the cat
ileum. The Physiologist 21:108,
1978.
24. Granger,
D.N., J.C. Parker, and A.E. Taylor.
Permselectivity of visceral exchange vessels to endogenous
macromolecules. Microvasc. Res.
17:5105, 1979.
25. Parker,
J.C., R.E. Parker, D.N. Granger, and A.E. Taylor. Effect of volume loading on interstitial albumin exclusion in the
lung. Fed. Proc. 38:1264, 1979.
26. Parker,
J.C., R.E. Parker, D.N. Granger, and A.E. Taylor. Effect of volume loading on interstitial albumin exclusion in the
lung. Fed. Proc. 38:1264, 1979.
27. Taylor,
A.E., J.C. Parker, R.E. Parker, and D.N. Granger.
Permselectivity of pulmonary capillaries to
endogenous macromolecules. Fed. Proc.
38:1327, 1979.
28. Moffatt,
D.S., J.C. Parker, and A.C. Guyton.
Measurement of pulmonary extravascular volume by constant infusion
thermadilution technique. Fed. Proc.
38:1327, 1979.
29. Falgout,
H.J., and J.C. Parker. The effect of volume
loading on interstitial albumin excluded volume in the lung. Ala. J. Med. Sci. 16:43, 1979.
30. Parker,
J.C., and A.E. Taylor. Effect of
increased pulmonary vascular pressure on albumin excluded volume in the
lung. Physiologist 22:98, 1979.
31. Rutili,
G., D.N. Granger, N.A. Mortillaro, J.C. Parker, and A.E. Taylor. Analysis of blood-lymph transport in resting
and passively flexed dog hing leg. Physiologist
22:110, 1979.
32. Taylor,
A.E., J.C. Parker, and D.N. Granger.
Convective and diffusive transport of endogenous proteins in lung
lymph. Physiologist 22:122,
1979.
33. Grimbert,
F.A., J.C. Parker, D.N., Granger, and A.E. Taylor. Lung vascular permeability changes following acid aspiration:
Effect of altering plasma protein concentration. Physiologist 22:48, 1979.
34. Granger,
D.N., N.A., Mortillaro, P.R. Kvietys, and J.C. Parker. Effects of volume absorption on intestinal
exclusion of albumin in the small bowel.
Physiologist 22:47, 1979.
35. Rutili,
G., P. Kvietys, J.C. Parker, and A.E. Taylor.
Studies of lung protein flux and water content in ANTU-induced pulmonary
edema. Microvascular Research
20:125, 1980.
36. Parker,
J.C., G. Rutili, D.N. Granger, and A.E. Taylor. Endogenous protein composition of right duct (RD) and prenodal (TB)
lung lymph in the dog. Microvascular
Research 20:123, 1980.
37. Parker,
J.C., G. Rutili, and A.E. Taylor.
Relationship of interstitial fluid volume to lymph flow in edematous
lungs. Fed. Proc. 39(3):485,
1980.
38. Rutili,
G., D.N. Granger, N.A. Mortillaro, J.C. Parker, and A.E. Taylor. Analysis of blood-lymph transport in resting
and passively flexed dog hing leg. Physiologist
22:110, 1979.
39. Ryan,
K., P. Kvietys, J.C. Parker, and A.E. Taylor.
Comparison of venous occlusion and isogravimetric capillary pressures in
isolated dog lungs. Physiologist
23:76, 1980.
40. Parker,
J.C., and A.E. Taylor. Effect of fluid
volume expansion on intralobar interdependance. Physiologist 23:77, 1980.
41. Holloway,
H., P. Kvietys, J. Downey, J.C. Parker, and A.E. Taylor. Estimation of pulmonary capillary pressure
in intact dog lungs. Fed. Proc.
40:449, 1981.
42. Parker,
J.C., P.S. Kinnebrew, R. Allison, and A.E. Taylor. Effect of hemorrhage and E. coli endotoxin on pulmonary
vascular permeability. Fed. Proc.
40:449, 1981.
43. Parker,
J.C., R. Allison, and A.E. Taylor.
Partitioning of filtration and protein transport between capillary pore
populations in the lung. Microvasc.
Res. 21:253, 1981.
44. Parker,
J.C., and A.E. Taylor. Extravascular
fluid compartmentation and lymph flow in edematous lungs. Proc. Int. Lymphology Soc., 1981.
45. Taylor,
A.E., R.C. Allison, and J.C. Parker.
Estimation of total protein diffusive flux across pulmonary
capillaries. Physiologist 24:19,
1981.
46. Parker,
J.C., R.C. Allison, and A.E. Taylor.
Total lung lymph flow in normally hydrated dog lungs. The Physiologist 24:17, 1981.
47. Allison,
R., J.C. Parker, and A.E. Taylor.
Effect of air embolization on termal dye estimates of extravascular lung
water. The Physiologist 24:18,
1981.
48. Taylor,
A.E., M.A. Perry, D.W. Shin, D.N. Granger, and J.C. Parker. Calculation of the effective pore radii in
dog hind-paw capillaries using lymph endogenous proteins. Microvasc. Res. 23:276, 1982.
49. Parker,
J.C., F. Grimbert, G. Rutili, and A.E. Taylor.
Pulmonary lymph plasma oncotic pressure gradients after hemodilution,
increased vascular pressures, and albumin infusion. In: Recent Advances in Microcirculatory Research (Ed.) P.
Gaethtgens, S. Karger, Basel., pp. 251-254, 1981.
50. Martin,
D., D.N. Granger, J. McCord, J.C. Parker, and A.E. Taylor. The protective effects of superoxide
dismutase on pulmonary endothelial damage associated with ANTU. Microvasc. Res. 23:265, 1982.
51. Martin,
D., J.C. Parker, and A.E. Taylor.
Comparison of right duct (RD) and tracheobronchial (TB) lymphatic flows
and protein concentrations in the dog. Fed.
Proc. 41:1245, 1982.
52. Allison,
R.C., R. Parker, J.C. Parker, and A.E. Taylor.
Thermal volume estimates of total lung mass in isolated dog lobes. Fed Proc. 41:1362, 1982.
53. Parker,
J.C., D. Martin, and A.E. Taylor.
Interstitial exclusion of albumin and globulin in the dog lung. Microvasc. Res. 23:268, 1982.
54. Parker,
J.C., M.P. Houston, D. Martin, and A.E. Taylor. Effect of hypoxia on the distribution of pulmonary vascular
resistance in the lung. Fed. Proc.
41:1246, 1982.
55. Taylor,
A.E., J.C. Parker, M. Perry, and D.W. Shin.
Estimation of pore dimensions in lung capillaries following ANTU
challenge. Fed. Proc. 41:1246,
1982.
56. Parker,
J.C., D. Martin, G. Rutili, and A.E. Taylor.
Prevention of free radical mediated vascular permeability increases in
lung using superoxide dismutase. Chest
83:525-535, 1983.
57. Parker,
J.C., B. Rippe, and A.E. Taylor.
Interstitial distribution of charged macromolecules in the lung. Microvasc. Res. 3:251, 1983.
58. Parker,
J.C., G. Rutili, and A.E. Taylor.
Comparison of crystalloid and colloid infusion on pulmonary fluid
balance during increased pulmonary vascular permeability. Physiologist 25:205, 1982.
59. Martin,
D., J.C. Parker, and A.E. Taylor.
Effects of dimethylsulfoxide (DMSO) and catalase on the protein
permeability of dog lung capillaries damaged with a-naphthylthiourea
(ANTU). Physiologist 25:204,
1982.
60. Taylor,
A.E., D. Martin, and J.C. Parker.
Effects of leukocyte reduction on lung vascular permeability changes
associated with a-naphthylthiourea (ANTU) endothelial damage. Physiologist 25:204, 1982.
61. Taylor,
A.E.., B. Rippe, R.C. Allison, and J.C. Parker. Osmotic reflection coefficient for total protein in an isolated
dog lung lobe. Fed. Proc.
42:1273, 1983.
62. Allison,
R.C., B. Rippe, J.C. Parker, and A.E. Taylor.
ANTU increased permeability in isolated dog lung lobes. Fed. Proc. 42:1108, 1983.
63. Martin,
D.J., J.C. Parker, and A.E. Taylor.
Effect of fructose 1-6, diphosphate (FDP) on the pulmonary vascular
damage associated with alpha-naphthylthiourea (ANTU). Fed. Proc. 42:1108, 1983.
64. Davidson,
L., A.E. Taylor, D. Martin, and J.C. Parker.
The effect of ibuprofen on lung vascular permeability associated with
ANTU damage. Fed. Proc. 42:1108,
1983.
65. Parker,
J.C., L.H. Campbell, and A.E. Taylor.
Failure of myocardial ischemia to acutely increased microvascular
permeability in the lung. Fed. Proc.
42:1106, 1983.
66. Rippe,
B., R.C. Allison, J.C. Parker, and A.E. Taylor. Effects of histamine, serotonin, and norepinephrine on vascular
resistances, pressures, and volumes and on capillary permeability in isolated
left lower lung lobes. Fed. Proc.
42:733, 1983.
67. Parker,
J.C., D. Martin, D.N. Granger, and A.E. Taylor. Estimates of interstitial "equivalent pore" dimensions
in normal and edematous dog lungs. Int.
J. of Microcirc. 2(3):271, 1983.
68. Parker,
J.C., B. Rippe, and A.E. Taylor. A
mathematical model of the pulmonary circulation: effect of histamine (H),
serotonin (5HT), norepinephrine (NE), and increased vascular pressure (IP). Physiologist 26:36, 1983.
69. Rippe,
B., J. Parker, and A.E. Taylor. Effects
of reduced plasma proteins on capillary filtration coefficients and
isogravimetric capillary pressures in isolated dog lungs. Physiologist 26:8, 1983.
70. Parker,
J.C. and A.E. Taylor. Plasma-lymph
transport and interstitial distribution volumes of charged macromolecules. Proc. Int. U. Physiol. Sci. 15:487,
1983.
71. Gilchrist,
S.A., J.C. Parker, and A.E. Taylor.
Extravascular distribution volumes (VA) of charged macromolecules in the
lung. Microvasc. Res. 27:244,
1984.
72. Rippe,
B., J.C. Parker, J. Thigpen, R.J. Korthuis, M. Townsley, and A.E. Taylor. Effect of high vascular pressures on
capillary filtration coefficient (Kf,c) in the lung. Microvas. Res. 27:260, 1984.
73. Parker,
J.C., B. Rippe, M. Townsley, and A.E. Taylor.
Effect of peak airway pressure (PAW) on microvascular permeability in
the lung. Fed. Proc. 43:513,
1984.
74. Allison,
R.C., J.C. Parker, and A.E. Taylor.
Effect of air microemboli on pulmonary vascular permeability in
dogs. Fed. Proc. 43:1028, 1984.
75. Parker,
J.S. Exclusion and charge effects in
lung interstitium. Int. J. Microcirc.
3:459, 1984.
76. Parker,
J.C., J.T. Cartledge, and G. Longnecker.
Periods of high peak airway pressure (PAW) can decrease protein sieving
by pulmonary capillaries. Fed. Proc.
44:1905, 1985.
77. Parker,
J.C., J.T. Cartledge, and A.E. Taylor.
Edema affects interstitial resistance to fluid filtration in the
lung. Microvasc. Res. 29:245,
1985.
78. Premen,
A.J., P.R. Kvietys, and D.N. Granger. Effects
of intestinal hormones on jejunal blood flow.
Fed. Proc. 44:205, 1985.
79. Rippe,
B., J.C. Parker, M. Townsley, R.J. Korthuis, and A.E. Taylor. High left atrial pressures, marked plasma
protein reductions and oleic acid or ANTU infusions cause increases in
pulmonary hydraulic conductivity; histamine and 5-HT do not. Int. J. Microcirc. 3:302, 1984.
80. Townsley,
M.I., J.C. Parker, R.J. Korthuis, and A.E. Taylor. The effect of decreases in lung mass on the pulmonary capillary
filtration coefficient (Kf,c) and hemodynamics. Microvasc. Res. 29:254, 1985.
81. Townsley,
M., R. Korthuis, J.C. Parker, and A.E. Taylor.
Effects of methylprednisolone on pulmonary vascular resistance and capillary
pressure in isolated lungs during active vasoconstriction. Int. J. Microcirc. 4:214, 1985.
82. Parker,
J.C., J.A. Cartledge, A.E. Taylor, and M.I. Townsley. Hydraulic conductivity of subcutaneous and pulmonary interstitium
during edema. The Physiologist
28:349, 1985.
83. Pitt,
R. and J.C. Parker. Decreased capillary
protein sieving after scald burn. Proc.
Am. Burn Assn., 1986.
84. Barman,
S.A., P.J. Coker, J.C. Parker, J.L. Ardell, and A.E. Taylor. Measurement of upper airway regional blood
flow in the isolated canine lung. Fed.
Proc. 46:516, 1987.
85. Parker,
J.C. Theoretical effect of molecular
charge on microvascular permeability to lactate dehydrogenase (LDH) isozymes in
dog lungs. Microvasc. Res.
33:111, 1987.
86. Cope,
D.K., J.C. Parker, M.D. Taylor, K.T. Marble, and A.E. Taylor. Site of hypoxic pulmonary vasoconstriction
in dog and human lungs. Southern
Soc. Anesth, 1988.
87. Parker,
J.C., T. Leach, P. Coker, L. Hernandez, A. Taylor, S. Barman, and R. Pitt. Pulmonary capillary filtration coefficients
during edema and varied perfusate protein concentration (CP). Physiologist 30(4):145, 1987.
88. Parker,
J.C., T. Leach, L. Hernandez, K. Adkins, K. Peevy, and P. Coker. Protamine increases pulmonary microvascular
permeability in the presence and absence of albumin and leukocytes. FASEB J. 2:A1293, 1988.
89. Peevy,
K.J., L.A. Hernandez, and J.C. Parker.
Barotrauma-associated microvascular injury after ventilation with short
inspiratory times and high flow rates. J.
Clin. Res. 36:80A, 1988.
90. Pitt,
R.M., J.C. Parker, and A.E. Taylor.
Starling force changes in burned tissue. Physiologist 30:218, 1987.
91. Parker,
J.C., L.A. Hernandez, T. Shibamoto, P. Coker, and B. Buchanan. Leukocyte mediation of protamine
microvascular damage in dog lungs. The
Physiologist 31:A58, 1988.
92. Shibamoto,
T., L.A. Hernandez, A. Moise, K. Peevy, A.E. Taylor, and J.C. Parker. Effect of hyperoxia and hypoxia on
paraquat-induced increases in pulmonary vascular permeability. The Physiologist 31:A59, 1988.
93. Adkins,
K., L. Hernandez, A. Moise, K. Peevy, B. Buchanan, and J.C. Parker. High peak airway pressures increase
microvascular permeability in adult rabbit lungs. The Physiologist 31:A59, 1988.
94.
Hernandez, L.A., K. Peevy, and J.C. Parker. Effect of high peak airway pressure on the normal rabbit
lung. FASEB J. 20:A1184, 1988.
95. Parker,
J.C., L.A. Hernandez, and K. Peevy.
Increased hydraulic conductivity in pulmonary and subcutaneous
interstitium induced by free radical injury and edema. Free Rad. Res. Comm. 5:204, 1988.
96. Shibamoto,
T., M. Ishibashi, V.R. Prasad, A.E. Taylor and J.C. Parker. Effect of blood flow on capillary filtration
coefficient (Kf,c) after paraquat injury (PQ) in isolated dog lungs. FASEB J. 3:A375, 1989.
97. Adkins,
W.K., M.I. Townsley, and J.C. Parker.
Estimation of the reflection coefficient in isolated rabbit lungs. FASEB J. 3:A1141, 1989.
98. Coker,
P.J., L.A. Hernandez, K.J. Peevy, and J.C. Parker. Effect of pulmonary surfactant depletion and mechanical
ventilation in the isolated rabbit lung.
FASEB J. 3:A1141, 1989.
99. Parker,
J.C., M.I. Townsley, L.A. Hernandez, B. Twohig, M. Perry, K. Adkins, and A.E.
Taylor. Allometric study of pulmonary
capillary filtration coefficient (Kf,c).
FASEB J. 3:A1141, 1989.
100. Hernandez,
L.A., K.J. Peevy, and J.C. Parker.
Response to mechanical ventilation after oleic acid induced lung
injury. FASEB J. 3:A1141, 1989.
101.
Ishibashi, M., R.K. Reed, M.I. Townsley, J.C. Parker, and A.E. Taylor. Permeability surface area (PS) products and
reflection coefficient (σ) at maximal protein diffusion in pulmonary
capillaries. The Physiologist
32:A201, 1989.
102.
Parker, J., M. Miniati, T. Shibamoto, and A. Taylor. Transcapillary Influx, Efflux, and Interstitial Equilibration of
Albumin in Dog Lungs. Proc. IUPS
XVII:178, 1989.
103.
Johnson, W.H., J.A. Young, L.A. Hernandez, J.C. Parker, and K.J.
Peevy. Positive End-Expiratory Pressure
(PEEP) Prevents Barotrauma-Induced Microvascular Injury due to High Peak
Inspiratory Pressure (PIP). Ped.
Res. 25:367A, 1989.
104.
Johnson, W.H., J.A. Young, J.C. Parker, and K.J. Peevy. High mean airway pressure exacerbates
barotrauma-induced microvascular injury in isolated perfused rabbit lungs. FASEB J. 4:A970, 1990.
105.
Coker, P.J., W.K. Adkins, L.A. Hernandez, and J.C. Parker. Lung maturity affects susceptibility to
pulmonary barotrauma in rabbits. FASEB
J. 4:A970, 1990.
106.
Hernandez, L.A., P. Coker, S. May, and J.C. Parker. Oleic acid induced changes in pulmonary
blood flow effects of ventilation. FASEB
J. 4:A970, 1990.
107. Ishibashi,
M., R.K. Reed, M.I. Townsley, J.C. Parker, and A.E. Taylor. Capillary-interstitial barrier properties to
albumin in the canine lung. FASEB J.
4:A589 (1990).
108.
Fujimoto, K., J.C. Parker, and S.G. Kayes. Effects of activated eosinophils on isolated perfused rat
lungs. Am. Rev. Resp. Dis.
141:A641, 1990.
109.
Parker, J.C., P.J. Coker, L.A. Hernandez, and J.A. Freeman. Perfusion Heterogeneity in Injured Lungs
Estimated Using Fluorescent Zinc-Cadmium Sulfide (ZCS) Aggregates. Physiologist. 33:A101, 1990.
110.
Shibamoto, T., S. Yoshikawa, and J.C. Parker. Fructose-1, 6-diphosphate augments paraquat-induced increases in
microvascular permeability in isolated dog lungs. Am. Rev. Respir. Dis. 143:A224, 1991.
111.
Parker, J.C., S. Roohparvar, J. Foster, L. Hernandez, and P. Coker. High peak inspiratory pressures (PIP) affect
the rate of bacterial clearance from rabbit lungs. Am. Rev. Respir. Dis. 143:A570, 1991.
112.
Fujimoto, K., J.C. Parker, S.G. Kayes, and S. Yoshikawa. O2 radical scavengers protect
against eosinophil-induced lung injury.
Am. Rev. Respir. Dis. 143:A40, 1991.
113.
Fujimoto, K., J.C. Parker, S. Yoshikawa, and S.G. Kayes. Eosinophils and supernatant injure isolated
perfused rat lungs. Proc. Fifth
World Congress for Microcirc., p. 29, 1991.
114.
Parker, J.C., R. Prasad, and W.V. Wojchiechowski. Capillary filtration coefficient (Kf,c)
using laser densitometry in isolated dog lungs. Proc. Fifth World Congress for Microcirc., p. 84, 1991.
115.
Reed, R.K., M. Ishibashi, M.I. Townsley, J.C. Parker, and A.E.
Taylor. Comparison of blood-to-tissue
clearance of tracer and endogenous albumin fluxes to determine PS product and reflection
coefficient (σ). Proc. Fifth
World Congress for Microcirc., p. 90, 1991.
116.
Whitehurst, R., K. Peevy, P. Coker, J. Parker, and W. Johnson. Overdistention, not high peak airway
pressure, produces pulmonary microvascular injury. J. Clin. Res. 38:93, 1990.
117. Fujimoto, K., J.C.Parker, S.G. Kayes, and
S. Yoshikawa. O2 radical scavengers protect against eosinophil-induced lung
injury. Am. Rev. Respir. Dis. 143:A40,1991.
118. Shibamoto, T., S. Yoshikawa, and J.C.
Parker. Fructose-1,6-diphosphate augments paraquat induced increases in
microvascular permeability in isolated dog lungs. Am. Rev. Respir. Dis. 143:A224, 1991.
119. Parker, J.C., S. Roohparvar, J. Foster, L.
Hernandez, and P. Coker. High peak inspiratory pressures (PIP) affect the rate
of bacterial clearance from rabbit lungs.
Am. Rev. Respir. Dis.
143:A570.1991.
120. Yoshikawa,S., J.C. Parker, A.F. Seibert,
and S.G. Kayes. The peroxide H2O2-halide system contributes to eosinophil
induced injury in isolated perfused rat lungs. FASEB J. 6:A1058, 1992.
121. Parker, J.C., S. Yoshikawa, S.G. Kayes,
A.G. Brady, and S. Martin. sialodacryoadenitis virus increases eosinophil
induced damage in isolated rat lungs. FASEB J. 6:A1612, 1992.
122. Cavanagh, K., J.C. Parker, F. Hill, and
W.V. Wojceichowski. Regional tracheal blood flow during high frequency jet
ventilation (HFJV) in juvenile pigs. FASEB
J. 6:A2043, 1992.
123. Yoshikawa,S., J.C. Parker, and S.G. Kayes.
Eosinophil peroxidase (EPO) inhibition and bromide modulate eosinophil induced
injury in isolated perfused rat lungs. Am.
Rev. Respir. Dis. 145:A279,1992.
124. Parker, J.C. Pulmonary capillary filtration
coefficients (Kf,c) estimated using zero-time and longer rates of lung weight
gain. FASEB J. 7:A898, 1993.
125. Parker, J.C., S. Payne, J. Fountain, A.E.
Taylor, and S. Martin. Neutrophil and eosinophil contributions to
ischemia/reperfusion in rat lungs. FASEB J. 7:A570, 1993.
126. Parker, J.C., J.A. Ardell, C.R. Hamm, M.I. Townsley,
and P.A. Coker. Gravity dependent and independent pulmonary blood flow
gradients in unanesthetized dogs. Proc. 17th Congr. I.U.P.S., Wednesday,
1993, pg.178.
127. Anglade, D.J., Corboz, M., Nazir, S.,
Menaquar, A., Parker, J.C., and Grimbert, F.A. Flow vs venous pressure effects
on filtration coefficient in oleic acid injured lungs. Proc. 17th Congr.
I.U.P.S. Monday, 1993, pg.54.
128. Yoshikawa,S., J.C. Parker, S.G. Kayes and
S. Martin. Pulmonary eosinophilia increases vascular and airway reactivity in
rats. FASEB J. 8:A684, 1994.
129. Parker, J.C., J.A. Ardell, C.R. Hamm, M.I.
Townsley, and P.A. Coker. Fractal properties and gravity dependent gradients of
pulmonary blood flow in exercising dogs. FASEB J. 8:A914, 1994.
130. Zayek, M. M., C. R. Hamm, K.J. Peevy, P.J.
Coker, and J. C. Parker. Endogenous nitric oxide (NO) is vital for survival of
pigs with oleic acid. FASEB J. 9:A764, 1995.
131. Parker, J. C., S. Yoshikawa,S., S. L.
Martin, and S.G. Kayes. Eosinophil induced vascular and airway remodelling and
hyperresponsiveness in rat lungs. FASEB J. 9:A432, 1995.
132. Parker, J.C., J.A. Ardell, C.R. Hamm, S. G.
Williams, and C. B. Cave. Simulation of regional blood flow gradients and
fractal properties in dog lungs. Microcirculation. 2:97,1995.
133. Parker, J.C., C.R. Hamm, and C. B. Cave.
Altered blood flow gradients and heterogeneity at increased flow in isolated
rabbit lungs. FASEB J. 10:A101, 1996
134. Hamm, C.R., J.C. Parker, and P. J. Coker.
Blood flow redistribution after phorbol myristate acetate (PMA) induced injury
in isolated piglet lungs. FASEB J. 10:A101, 1996
135. Parker, J.C., E.C. Breen, and J.B. West.
Basement membrane collagen gene expression increases in rat lungs at high
inflation pressures. Am. J. Respir. Crit. Care Med. 153:A196, 1996.
136.
Parker, J.C., E.C. Breen, and J.B. West. Mechanical stress increases
expression of mRNA for microvascular interstitial matrix proteins in rat lungs Circulation
94(8): I-231 (Suppl.), 1996.
137. Parker, J.C. and C. Ivey. Alveolar flooding
increases capillary filtration after vascular pressure induced stress failure
in isolated rat lungs. FASEB J. 11:A129, 1997.
138. Parker, J.C. Phosphotyrosine phosphatase
inhibition increases susceptibility of rat lungs to airway pressure induced
injury. Am. J. Respir. Crit. Care Med. 155: A88,1997.
139. Parker, J.C., C. Ivey and J. Allan Tucker.
Gadolinium prevents high airway pressure induced permeability increases in
isolated rat lungs. FASEB J. 12:A26, 1998.
140. Hamm, C. R., J.C. Parker and C. B. Cave.
Altered fractal dimension (Ds) and distance correlation (ρxyz)
of regional blood flow in oleic acid injured rabbit lungs. FASEB J. 12:A988,
1998.
141. Anglade, D.J., M. Corboz, A. Menaquar, J.C.
Parker, S. Bayat, G. Benchetrit, and F. A. Grimbert. Blood flow elevation
increases filtration coefficient more venous pressure elevation in acute lung
injury. Am. J. Respir. Crit. Care Med. 157: A349, 1998.
142. Parker, J.C., R.N. Lausch, X.T. Yan, F.G.
Eyal, C.R. Hamm, and Sherri L. Martin. High airway pressure stress induces
cytokine release from perfused mouse lungs. Proc. Of the 1999 Biomed. Eng.
Conf. 42:427-428, 1999.
143. Parker, J.C., T. Stevens, and Sherri L.
Martin. Vascular segmental permeability after high peak inflation pressure
(PIP) injury in isolated rat lungs. FASEB J. 14:A605, 2000.
144. Parker, J.C., J. Thomas, and C. R. Hamm.
Optimized blood gases during total liquid ventilation in piglets. FASEB J. 14:A609, 2000.
145. Parker, J.C., and T. Stevens. Mechanical
stress induced calcium transients in rat pulmonary artery and Microvascular
endothelial cells. FASEB J. 14:A693, 2000.
146. Parker, J.C. Ventilator induced lung injury
(VILI) attenuated by inhibitors of myosin light chain kinase and calmodulin.
Am. J. Respir. Crit. Care Med. 161:A212, 2000.
147. Parker, J.C. Hydraulic conductance (Lp) in
pulmonary artery and microvascular endothelial monolayers. FASEB J. 15:A158,
2001.
148. King, J., T. Weatherington, J. Creighton,
F. McDonald, M. Gillespie, J. Olson, J. Parker, and T. Stevens.
Characterization of phenotypically distinct endothelial cell populations from
rat lungs. FASEB J. 15:A492, 2001.
149. Parker, J.C., T.Stevens, J.Randall, C.
Sybert, S. Yoshikawa, and A. Penton. Hydraulic conductance of segmental
endothelial phenotypes in pulmonary circulation. Proc. 7th World
Congress for Microcirculation. pp. 505-511, 2001
150. Eyal, F.G., C.R. Hamm, P. Coker-FLowers, M.
Strober, and J.C. Parker. Inhibition of macrophages with gadolinium chloride
markedly attenuates the respiratory failure of the surfactant deficient lung.
Ped. Res. 51: 345A, 2002.
151. Parker, J.C., S. Yoshikawa, C. R. Hamm, F.
G. Eyal. Enhanced Gas Exchange During Alveolar Flooding Using a Dual Flow
Liquid Ventilation System in Piglets. FASEB J. 16: A836, 2002.
152. Yoshikawa, S., C. Sybert, F. G. Eyal and J.
C. Parker. Ventilator Induced Hyperpermeability in Mouse Lungs Measured by an
Albumin ELISA FASEB J. 16: A410, 2002.
153. Eyal, F.G., C. R. Hamm, P. Coker-Flowers,
M. Strober and J.C. Parker. The neutralization of alveolar macrophages reduces
barotrauma induced lung injury. FASEB J. 16: A410, 2002.
154. Parker, J. C., T. D. Barnett, C. R. Hamm
and F.G. Eyal. Enhanced clearance of albumin solution from piglet lungs using tidal
and bias flow liquid ventilation. Am. J. Respir. Crit. Care Med. 165:A788,
2002.
155. Yoshikawa, S., .C. Parker, C. Sybert, F.
Eyal, and R. N. Lausch. Ventilator
induced lung albumin leak and MIP-2 production independent of TNFα effect in
intact mice. Am. J. Respir. Crit. Care Med. 165:A787, 2002.
156. Parker, J.C., D.A. Drake, J.A. King, and S.
Yoshikawa. Ventilator induced lung injury-Leak sites identified using
methacrylate vascular casts. Am. J. Respir. Crit. Care Med. 167: A774, 2003
157. Yoshikawa, S., S.D. Reynolds, and J.C.
Parker Ventilator induced lung injury detected by plasma levels of Clara Cell
Specific Protein in mice. . Am. J. Respir. Crit. Care Med. 167:
A775, 2003
158. Drake, D.A., S. Yoshikawa, J.A. King, and
J.C. Parker. Vascular leak sites
identified using methacrylate casts after high airway pressure injury. FASEB J.
17:A135, 2003
159. Parker, J..C., G. T. Miller, S. B. Tarpey,
M. Anghelescu, A. M. Penton, and T. Miyahara. Junctional proteins reduced in
lung endothelial cells by plasma membrane wounding. FASEB J., 2004
160. Anghelescu, M., S. Tarpey, T. Miyahara, A.
Penton, G. Miller and J.C.Parker. Differential expression of potassium channels
in lung endothelial cell phenotypes. FASEB J., 2004
161. Parker, J..C., G. T. Miller, S. B. Tarpey,
M. Anghelescu, A. M. Penton, and J. B. Adkison. Cell wounding modulates
junctional proteins in rat pulmonary artery and microvascular endothelial
cells. Am. J. Respir. Crit. Care Med. 169: A158, 2004
162. Chekuri, A., S. David , A. Sakla, F.
Donovan and J. C. Parker. Simulated control algorithm for total liquid
ventilation. Proc. 3rd Gulf Coast Physiology Society. March,5 2004.
163. David , Selvan, Anu Chekuri, Adel Sakla,
Frank Donovan and James C. Parker. Controller for a total liquid ventilation
pumping system. Proc. 3rd Gulf Coast Physiology Society. March,5
2004.
164. Miller, Greg T., Siobhan B. Tarpey, Mircea
Anghelescu, Anna M. Penton, and James C. Parker. Cell wounding modulates
junctional proteins in rat pulmonary artery and microvascular endothelial
cells. Proc. 3rd Gulf Coast
Physiology Society. March,5 2004.
165. Parker, J.C., Sawako Yoshikawa, Takashige
Miyahara, Susan D. Reynolds, Barry R. Stripp, Mircea Anghelescu, and Fabien G.
Eyal. Clara cell secretory protein and
phospholipase A2 activity modulate acute ventilator induced lung
injury in mice. FASEB J. 19: A172, 2005
166.
Miyahara, T., M. Anghelescu, and J. C. Parker. The effects of
phosphoinositide 3-OH kinase on
ventilator induced lung injury in isolated mouse lungs. FASEB J. 19: A174, 2005
167. Anghelescu, M., T. Miyahara, and J. C.
Parker. Activation of TRPV4 in the microvessels of isolated rat lung. FASEB J.
19: A126, 2005
INVITED PAPERS AND ABSTRACTS:
1. December 9-13, 1978. Postgraduate assembly of New York Society of
Anesthesiologists. Symposium on lung fluid balance.
2. Seminar at Albany Medical College, Department
of Physiology, 6/16/80.
3. August 1978, Seminar on vertical distribution
of lung water, Resp. Disease Unit, St. Paul's Hospital,
Vancouver, B.C.
4. 1979, Int. Conf. on Lung Water, University of
B.C. School of Medicine, Vancouver, B.C.
5. Gordon Research Conference, Plymouth, NH,
June 9-13, 1980. Invited discussant,
"Excluded volumes in lung
tissue".
6. Visiting professor, Department of Physiology,
Albany Medical College, Albany, NY, June 16, 1980,
"Albumin excluded volume in the lung".
7. European Conference for Microcirculation,
Garmisch, West Germany, September, 15-16, 1980, "Oncotic buffering in the lung after hemodilution, albumin
infusion and elevated pressure".
8. Visting professor, Institute of Medical
Physiology, Copenhagen, Denmark, September 25-26, 1980, "Permeability of lung vessels to
macromolecules".
9. Visiting professor, Institute of Physiology,
Bergen, Norway, September 29-30, 1980, "Albumin excluded volumes in the lung".
10. Pharmacia Travel Award lecture, Department
of Experimental Medicine, Pharmacia AP, Uppsala, Sweden, October 3, 1980, "Estimates of permeability
coefficients in the lung using lymph protein
fluxes".
11. Visiting professor, Respiratory Disease
Unit, John Radcliffe Hospital, Oxford, England,
October
8, 1980, "Albumin excluded volume and transcapillary fluxes in the
lung".
12. Nordic Microcirculatory Society, Geilo,
Norway, February 4-7, 1981,
"Estimates of interstital 'equivalent
pore' dimensions in normal and edematous lungs".
13. Visiting professor, Department of
Physiology, University of Goteborg, Sweden, February 16, 1981, "Vascular permeability in
the lung".
14. Visiting professor, Department of Surgery,
Sahlgrenska Hospital, Goteborg, Sweden, February 17, 1981, "Studies on vascular permeability in the
lung".
15. IUPS XXIXth Congress, Sydney,
Australia,"Plasma-lymph transport and distribution of cahrged macromolecules," 8/28/83-9/3/83.
16. Third World Congress for
Microcirculation. Symposium on the
Interstitium. "Exclusion and change effects in the
lung". September 9-14, 1984. Oxford, England.
17. Am. Burn Assoc., Chicago, IL., April, 1986,
"Decreased capillary protein sieving after
scald
burn".
18. FASEB, Biomedical Engineering Society
Symposium on Quantitative Analysis of Lung Fluid Balance. "Interstitial distribution of charged
macromolecules in the dog lung: A kinetic model",
St. Louis, MO., April, 1986.
19. Sixth European Congress on Diseases of the
Chest. Tel Aviv, Israel,
"Capillary filtration and macromolecular
permeability in the lung", June 16-20, 1986.
20. Satellite Symposium IUPS on
Interstitial-Lymphatic Solute and Water Movement. Victoria, British
Columbia, Canada. "Transvascular
transport and interstitial distribution volumes of charged macromolecules in normal and injured lungs",
July 21-25, 1986.
21. Fourth World Congress for Microcirculation,
Tokyo, Japan. "Pulmonary
microvascular permeability to
differently charged isozymes of lactate dehydrogenase", July 26-August 2, 1987.
22. Symposium organizer, "Charge related
selectivity of continous capillary beds", APS Fall meeting, San Diego, CA, October 12-15, 1987.
23. Visiting professor, "Effect of charge
on microvascular permeability", Department of Physiology, Univ. of Arizona, Tucson, AZ, May 7,
1988.
24. Invited Speaker, "Increased
transcapillary filtration during hydrostatic pulmonary edema". International
School of Thoracic Medicine course on "Interstitium, pleural space, and lymphatics". Ettore Magorana Centre, Erice, Sicily, Italy, 9/29/88-10/5/88.
25. IUPS XXXI Congress, Helsinki, Finland, July
9-14, 1989,"Transcapillary influx, efflux and interstitial equilibration of albumin in dog lungs".
26. Symposium speaker, "Role of bronchial
circulation and pulmonary circulation in lung liquid and protein exchange", XXXI IUPS
Leningrad Satellite Symposium, Leningrad, U.S.S.R., 7/17/89-7/19/89.
27. Invited speaker, "Measurement of
capillary permeability using tissue and lymph protein clearances".
Conferences de la Commission de la Recherche, Faculte de Medicine de Grenoble, Grenoble, France, 28
November 1989.
28. Seminar in French, "Desertion
capillaire dans le poumon lese" (Capillary derecruitment in the injured lung), La reunion
scientifique du laboratoire de physiologie, Faculte de Medicine de Grenoble, Grenoble, France, 14 December
1989.
29. Invited speaker, "Pulmonary barotraume
due to mechanical ventilation", Institute of Clinical Pulmonary Pathophysiology of the C.N.R.,
University Hospital, Palermo, Italy, 20 November 1989.
30.
Visiting Professor, Department of Surgical Research, University of
Mannitoba, Winnipeg, Manitoba, Canada,
August 1990.
31.
Invited speaker, "Pulmonary capillary filtration coefficient using
laser densitometry," Department of Human Physiology, University of
California at Davis, Davis, CA, 9 May 1991.
32. Invited
speaker, "High volume stress failure of pulmonary capillaries,"
Matsumoto High Altitude Medicine Conference, Matsumoto, Japan, September 31,
1991.
33. Invited speaker for two lectures,
"Ventilation induced stress failure of pulmonary capillaries", and
"Eosinophil induced lung damage in rats." Departments of Pediatrics
and Cardiaolgy, Univ. of Utah, Salt Lake City, UT, Feb. 1992.
34. IUPS XXVII Congress, Glascow, Scotland,
"Gravity dependent and independent pulmonary blood flow gradients in
unanesthetized dogs," August 1993.
35. Seminar speaker, “Altered fractal dimension
(Ds) and distance correlation (ρxyz) of regional blood flow in
oleic acid injured rabbit lungs.” Department of Physiology, University of Washington, Seattle, WA, April 24,
1998.
36.Invited speaker, “Factors affecting vascular
permeability during ventilator associated lung injury,” International consensus conference on
intensive care medicine, Toronto, Ont., Oct. 29-31,1998.
37. Symposium speaker, “Pharmacologic modulation
of ventilator induced lung injury,” Am. Thoracic Soc. International Conference,
San Diego, CA, April 26, 1999.
38. Symposium speaker, “High airway pressure
stress induces cytokine release from perfused mouse lungs,” 1999 Biomedical
Engineering Conference, Big Sky, MT. June 16-20, 1999.
39. Seminar speaker, “Mechanisms of ventilator
induced lung injury,” Dept. of Pulmonary and Critical Care Medicine, Mayo
Clinic, Rochester, MN, 11/10/00.
Revised 03/28/05