CURRICULUM VITAE

 

James C. Parker

 

 

PERSONAL INFORMATION:

 

            Current Position Title:                           Professor                     

 

            Professional Address:                           University of South Alabama

                                                                        College of Medicine

                                                                        Department of Physiology

                                                                        MSB 3024

                                                                        Mobile, Alabama 36688

           

 

            Citizenship:                                           United States

 

           

EDUCATION:

 

High School Education:

 

            Metairie County Day School, Metairie, Louisiana -1957.

 

Undergraduate Education:

 

            B.S. - Biology & Chemistry - Washington and Lee University, Lexington, VA - 1961.

 

Graduate Education:

 

            Doctorate: Ph.D. - Physiology - University of Mississippi, Graduate School of

                        Medical Sciences, Jackson, Mississippi - 1972.

 

Honorary Awards:

 

            Dean's List; Honor Roll - Washington and Lee University.

            Pharmacia Travel Award of the Microcirculatory Society, 1981 - Funds for travel to

                        European Research Laboratories.

 

Fellowship Awards:

 

            Mississippi Heart Association Research Fellowship, 1973-74.

            NIH Predoctoral Fellowship, Cardiovascular Physiology, University of Mississippi

                        Medical Center, 1968-72.

            Mayo Research Foundation Fellowship, June-August 1963, Experimental Pathology.

 

PROFESSIONAL QUALIFICATIONS:

 

            National Committees and Offices:

 

            NIH CVA-AHR Cardiovascular and Pulmonary Study Section, Washington, D.C.,

                        February 13-15, 1979.

            Awards Committee, United States Microcirculatory Society, 1981-84, Chairman, 1983-84.

            Research Advisory Committee, Alabama Heart Association, 1983-86.

            NIH HLI Respiratory and Applied Physiology Study Section, Washington, D.C.,

                        1984 - 1987.

            Editorial Board,  J. Appl. Physiol., 1984-93.

            Reviewer; American Journal of Respiratory and Critical Care Medicine,

                        Circulation Research,    Microvascular Research, American Journal of Physiology,

                        Journal of  Applied. Physiology, Journal of Physiology (Lond.),

                        Journal of Clinical Investigation, Critical Care Medicine

            NIH Trauma and Burn Research Fellowship Review Committee, 1984.

            NIH NIGMS Site Visit Committee, 1986, 1987.

            NIH Program Project Review Site Visit, Seattle, WA, 1987.

            NIH Cancer Therapeutics Review Committee Site Visit, Richmond, VA., 1987.

            NIH ARDS SCOR Review Committee Site Visit, Seattle, WA, 1988.

            NIH NLS Review Committee Site Visit, San Francisco, CA, 1987.

            NIH Physiologic Sciences Study Section, Bethesda, MD March 1-3, 1995.

            NIH SBIR/STTR Study Section, Bethesda, MD 1999.

            NIH SBIR Study Section SSS-3, Chevy Chase, MD, Feb. 27-28, 2002

            Am. Heart Assoc. S. E. Region Peer Review Committee, Tampa, FL, April 7-9, 2002

            NIH NHLBI Program Project Review Committee, Bethesda, MD, May 8, 2002

            NIH Neuro SBIR ZRG1 BSCT 10 B study section, Bethesda, MD, Dec. 4, 2003

            Gulf Coast Physiologic Society. Treasurer. 2003-4.

            NIH NIGMS Trauma, burn and perioperative injury center study section. March 9-10, 2004

 

Professional Society Memberships:

 

            American Physiological Society

            Circulation and Respiratory Sections of American Physiological Society


            Microcirculatory Society

            Sigma Xi

            Lung Water Club

            International Lymphology Society

            Alabama Heart Association

            American Heart Association, Circulation Council

            North American Vascular Biology Organization

            New York Academy of Sciences

            American Thoracic Society

 

Past Professional Experience:

 

            Associate Professor, 1980-83, University of South Alabama, College of Medicine, Department of Physiology,

                        Mobile, Alabama.

            Assistant Professor, 1977-80, University of South Alabama, College of Medicine,

                        Department of Physiology, Mobile, Alabama.

            Assistant Professor, 1973-77, University of Mississippi Medical Center,

                        Department of Physiology, Jackson,      Mississippi.

            Research Associate, 1972-73, University of Mississippi Medical Center,

                        Department of Physiology and Biophysics, Jackson, Mississippi.

 

ACADEMIC QUALIFICATIONS:

 

Present Appointment:

            1983-Present - Professor, Department of Physiology

 

Faculty Teaching Assignments:

            Pulmonary Physiology:

            1979-Pres.- COM I Medical Physiology course                                  

            1980- Senior elective in Physiology

            1985-Pres.- Advanced Respiratory Physiology

            1981-Pres. - Advanced Cardiovascular Physiology

            1984- Pres. BEAR Physiology course for minority students.

            1990-Pres.-Journal Club

Hematology:                            

            1978    - COM I Medical Physiology course

Student Laboratories:   

            1978-Pres.- COM I Medical Physiology

            1985-Pres.Intro. to Laboratory Physiology

 

Committee Assignments:

            USAMC Research Advisory Committee, 1979-83

            Graduate Student Promotions Committee, 1982-85

            USAMC Medical School Admissions Committee, 1980-84, 1992-94 Ad Hoc

            American Heart Association, Alabama Afficliate Research Advisory Committee, 1982-86

            North American Microcirculatory Society Awards Committee, 1981-84; Chairman 1983-84

            USAMC Animal Health and Welfare Committee, 1984-87

            USAMC Radiation Safety Committee, 1984-87, 1996-1999

            USAMC Medical Student Summer Research Committee, 1983-87, Chairman, 1985-86

            USAMC Continuing Education Committee 1990-1991

            USAMC Committee on Ethics in Research 1991-1992

            USAMC Patent Committee 1993-1995, Chairman, 2003-5

            USAMC Faculty Committee on Appointments, Promotions, and Evaluations 1993-1995

            USAMC Biomedical Library Committee 1993-1995

            USAMC University Faculty Grievence Committee 1994-1997

            USAMC Curriculum Committee 1995-1998

            Alabama Regional Science Fair Judge 1992-1999

            USAMC Graduate recruiting committee 2003-4

 

Research Grants:

            As Principal Investigator:

NIH 2 R42 HL57040 - 02  Phase II STTR,“Airway perfusion assisted liquid ventilator”, 7/1/01-6/31/03, $500,000, J.C. Parker, P.I., $250,000 annual

NIH 1 P01 HL66299 Project 2, J. C. Parker, P.I.., $220,000 annual, In: “Lung endothelial cell phenotypes”, 12/01/01-11/31/06, $6,941,491, Troy Stevens, P.I.

            NIH 1 R01 HL66347 “Mechanical Injury to Lung Endothelium,” 12/1/2000

                                    -11/31/2005, $1,244,615, J.C. Parker, P.I., $248,923 annual.

            NIH 1 R41 HL57040-01A1 STTR, “Airway perfusion assisted liquid ventilator,”

                                    2/1/99-1/30/00, $105,000, J.C. Parker, P.I.

            American Heart Association, Southeast Affiliate, 98101 80SE,"Mechanical ventilation induced lung injury,"7/1/98-

                                   6/30/00, $70,000, J.C.Parker,P.I.  American Heart Association, #94013094, "Heterogeneity of

                                   pulmonary blood flow and injury". 7/1/94-6/30/97, $136,000, J.C.Parker, P.I.

            American Heart Association, #91011060, "Eosinophil and neutrophil effects

                                    on microvascular permeability in the lung,"7/1/91-6/30/94,$74,272,

                                    J.C.Parker, P.I.

            American Heart Association, Alabama Affiliate, AL-G-920030,"Tracheal blood

                                    flow during high frequency Jet Ventilation,"7/1/92-6/30/93,

                                    $25,000, J.C.Parker,P.I.                     

            NIH 1 RO1 HL37341, "Lung Microvascular Injury due to Airway Pressure",

                                    4/1/87-3/31/90, $197,271

            NIH 2 RO1 HL24571, "Interstitial Fluid Pressure and Excluded Volume in the

                                    Lung"; 8/1/79-7/31/82, $186,268; Renewal 8/1/82-7/31/87, $316,000;

                                    Renewal 8/1/87-7/31/92, $526,000;  J.C. Parker P.I.

            American Lung Association, "Interstitial Pressure and Excluded Volume in

                                    the Lung", 6/1/79-5/30/81, $25,666.

            American Heart Association, "Interstitial Pressure and Excluded Volume in

                                    the Lung", 7/1/79-6/30/82, $61,820.

            Intramural - University of South Alabama, 2/15/78-2/15/79, "Pulmonary Capillary

                                    and Interstitial Protein Transport", $5,000.

            Mississippi Heart Association, "Dynamics of Pulmonary Vascular and Extravascular Forces", 6/1/77-5/31/79,

                                    $18,974 (not transferred).

            Mississippi Heart Association, "Energy Metabolism in

                                    the Ischemic Myocardium", 6/1/75-5/31/77, $16,780.

 

            As Co-Investigator:

NIH R01 HL67461-01.,”Tlymphocyte role in lung ischemia - reperfusion injury.”, 4/1/01-2/28/05, $200,000/yr., (A. E. Taylor, P.I.; J.C. Parker, 20% effort).

NIH R01 HL63302-01A2 “Airway submucosal glands and cystic fibrosis disease” 4/1/01-3/31/06, $1,486,263 (Stephen T. Ballard, P.I.; J.C. Parker, 5% effort)

NIH 1 P01 HL66299 Project 2, J. C. Parker, P.I.., $220,000 annual, In: “Lung endothelial cell phenotypes”, 12/01/01-11/31/06, $6,941,491, Troy Stevens, P.I.

            American Lung Association, "Diaphragmatic function during

                                    mechanical ventilation in ewes.", $50,000 (Max Ferrigno,

                                    P.I., 7/1/95-6/30/97; J.C. Parker, 15%).

            American Heart Association, Alabama Affiliate, "Nitric Oxide

                                    Modulation of Oleic Acid Injured Lungs,"7/1/95-6/30/97,

                                    $55,450, (Michael M. Zayek, P.I; J.C.Parker, 10% effort. NIH, "Transport Across Alveolar

                                    Capillary Membrane", 9/1/77-8/31/82, $200,715;

                                    renewal 9/1/81-8/31/87, $545,000 (A.E. Taylor, P.I.).  (Renewal

                                    9/1/87-8/31/92, $640,000; J.C. Parker, 15%).

            Parker B. Francis Foundation Fellowship, 9/1/78-8/31/81, $72,000; renewal

                                    9/1/81-8/31/83, $72,000 (A.E. Taylor, P.I.).

            American Lung Association, "Barotrauma and Microvascular Injury in the

                                    Immature Lung", $35,000 (Alicia Moise,P.I., 7/1/88-6/30/90;

                                    J.C. Parker, 15%).

 

Patents Awarded: U. S. Patent No. 5,706,830 awarded on Jan. 13, 1998, entitled “Liquid ventilator

                         and use thereof ”, to J.C. Parker, ref. No. 87647.97R243.

 

            Ph.D Dissertation Committees

                                    Michelle Lynn Perry                  1988

                                    William Keith Adkins                1991

                                    Peter S. Wilson                        1993

                                    Laura Trout                              2001

                                    Judy Creighton

                                    Donna Cioffi

                                    Diego Alverez

                                    Sarah Sayner

                                    Brad Swiger

 

            Post-Doctoral Students                                                

                                    Roger M. Pitt M.D.                                         

                                    Lucretia A. Hernandez M.D., Ph.D.     

                                    Toshishiga Shibamoto M.D., Ph.D.

                                    Keisaku Fujimoto M.D.,Ph.D.

                                    Sawako Yoshikawa M.D.,Ph.D.

                                    Mircea Anghelescu M.D.

                                    Siobhan Tarpey Ph.D.

                                    Tokashige Miyahara M.D., Ph.D.

 

            Medical Student Honors Program

                                    Jarrod Adkison B.Ch.E.

 

PUBLICATIONS:

 

TEXTBOOKS:

 

1.         Taylor, A.E., K. Rehder, R. Hyatt, and J.C. Parker.  Clinical Pulmonary Physiology, Saunders Publishing Co: Philadelphia, PA, 1989.

 

SCIENTIFIC PAPERS AND CHAPTERS:

 

1.         Jones, C.E., J.C. Parker, and E.E. Smith.  Determination of myocardial acid soluble adenine nucleotides on anion exchange thin layers. J. Chromatography 64:378-344, 1972.

 

2.         Parker, J.C., and E.E. Smith.  Effects of xanthine oxidase inhibition in cardiac arrest.  Surgery 71:339-344, 1972.

 

3.         Parker, J.C., C.E. Jones, and E.E. Smith.  Determination of acid soluble nucleosides and bases in myocardium by thin layer methods.  J. Chromatography 79:360-363, 1973.

 

4.         Guyton, A.C., A.E. Taylor, R.E. Drake, and J.C. Parker.  Dynamics of subatmospheric pressure in pulmonary interstitial

fluid.  In: Lung Liquids, a CIBA Foundation Symposium.  Elsevier, Amsterdam, 1976.

 

5.         Parker, J.C., C.E. Jones, and J.X. Thomas, Jr.  Effect of ischemia and infarction on regional content of adenine nucleotides and derivatives in canine left ventricle.  Cardiology 61:279-288, 1976.

 

6.         Parker, J.C., E.E. Smith, and C.E. Jones.  The role of nucleoside and nucleobase metabolism in myocardial adenine nucleotide regeneration after cardiac arrest.  Circulatory Shock 3(1):11-20, 1976.

 

7.         Jones, C.E., J.X. Thomas, J.C. Parker, and R.E. Parker.  Acute changes in adenine nucleotides, nucleotide derivaties and contractile force in ischemic and non-ischemic and canine myocardium following coronary occlusion.  Cardiovascular Research 10:275-282, 1976.

 

8.         Parker, J.C., and D.H. Pearce.  Computation of indicator dilution flows and transit times with a pocket calculator.  Am. Heart J. 91:826-827, 1976.

 

9.         Parker, J.C., C.E. Jones, J.X. Thomas, and H.J. Granger.  A dynamic analysis of energy and contractility transients in ischemic myocardium.  Proceedings of Summer Computer Simulation Conference, pp. 539-544, 1977.

 

10.       Parker, J.C., A.C. Guyton, and A.E. Taylor.  Pulmonary transcapillary exchange and pulmonary edema.  In: A.C. Guyton (ed.) International Review of Physiology, Cardiovascular Physiology III.  University Park Press, Baltimore, 1978.

 

11.       Parker, J.C., A.C. Guyton, and A.E. Taylor.  Pulmonary interstitial and capillary pressures estimated from intra-alveolar fluid pressures. J. Appl. Physiology 44:267-276, 1978.

 

12.       Guyton, A.C., J.C. Parker, A.E. Taylor, T.E. Jackson, and D.S. Moffatt.  Forces governing water movement in the lung.  In: Pulmonary edema.  A.P. Fishman and E.M. Renkin, eds., Am. Physiological Society, Bethesda, MD, 1979.

 

13.       Parker, J.C., and A.E. Taylor.  Pulmonary interstitial and capillary pressures estimated from intra-alveolar fluid pressures (Letter), J. Appl. Physiol. 47-643-644, 1979.

 

14.       Parker, J.C., A.E. Taylor, R.E. Parker, and D.N. Granger.  Vertical gradient in regional vascular resistance and pre- to post-capillary resistance ratios in the dog lung.  Lymphology 12:191-200, 1979.

 

15.       Parker, J.C., J.H. Falgout, R.E. Parker, D.N. Granger, and A.E. Taylor.  The effect of volume loading on interstitial albumin exclusion and lymph flow in the lung.  Circ. Res. 45:440-450, 1979.

 

16.       Granger, D.N., T. Miller, R.E. Allen, R.E. Parker, J.C. Parker, and A.E. Taylor.  Permselectivity of the cat blood-lymph barrier to endogenous macromolecules.  Gastroenterology 77:103-109, 1979.

 

17.       Granger, D.N., N.A. Mortillaro, P.R. Kvietys, G. Rutili, J.C. Parker, and A.E. Taylor.  Role of the interstitial matrix during intestinal volume absorption.  Am. J. Physiol. 238:G183-G189, 1980.

 

18.       Parker, J.C., R.E. Parker, D.N. Granger, and A.E. Taylor.  Vascular permeability and transvascular fluid and proteins transport in the dog lung.  Circ. Res. 48:549-561, 1981.

 

19.       Parker, J.C., H.J. Falgout, F.A. Grimbert, and A.E. Taylor.  The effect of increased vascular pressure on albumin excluded volume and lymph flow in the dog lymph.  Circ. Res. 47:866-875, 1980.

 

20.       Taylor, A.E., J.C. Parker, D.N. Granger, and G. Rutili.  Pulmonary edema: Changes in Starling Forces and Lymph Flow.  In: Tissue Fluid Pressure and Composition.  (Ed.) Alan Hargens, Williams and Wilkins Co., pp. 135-143, 1981.

 

21.       Perry, M.A., and J.C. Parker.  Indicator measurement of splanchnic blood flow.  In: Measurement of Blood Flow.  (Eds.) D.N. Granger and G.B. Bulkley, Williams and Wilkins Co., pp. 159-176, 1981.

 

22.       Parker, J.C., F. Grimbert, G. Rutili, and A.E. Taylor.  Pulmonary lymph plasma oncotic pressure gradients after hemodilution, increased vascular pressures, and albumin infusion.  In: Recent Advances in Microcirculatory Research (Ed.) P. Gaethtgens, S. Karger, Basel, pp. 251-254, 1981.

 

23.       Taylor, A.E., J.C. Parker, D.N. Granger, N.A. Motrillaro, and G.Rutili.  Assessment of capillary permeability using lymphatic protein flux: Estimation of the osmotic reflection coefficient.  In: The Microcirculation, (Ed.) R. Effros, H. Schmid-Schonbein, and J. Ditzel, Academic Press, pp. 19-32, 1981.

 

24.       Parker, J.C., R.C. Allison, and A.E. Taylor.  Edema affects intralveolar fluid pressures and interdependence in dog lungs.  J. Appl. Physiol. 51:911-921, 1981.

 

25.       Grimbert, F.A., J.C. Parker, and A.E. Taylor.  Increased pulmonary vascular permeability following acid aspiration. J. Appl. Physiol. 51:335-345, 1981.

 

26.       Kinnebrew, P.S., J.C. Parker, J.J. Falgout, and A.E. Taylor.  Pulmonary microvascular permeability following E. coli endotoxin and hemorrhage.  J. Appl. Physiol. 52:403-409, 1982.

 

27.       Rutili, G., P. Kvietys, J.C. Parker, and A.E. Taylor.  Increased microvascular permeability induced by ANTU.  J. Appl. Physiol. 52:1316-1323, 1982.

 

28.       Rutili, G., D.N. Granger, A.E. Taylor, J.C. Parker, and N.A. Mortillaro.  Analysis of lymphatic protein data IV.  Comparison of the different methods used to estimate reflection coefficients and permeability-surface area products.  Microvasc. Res. 23:347-360, 1982.

 

29.       Parker, J.C., M. Crain, F. Grimbert, G. Rutili, and A.E. Taylor.  Total lung lymph flow and fluid compartmentation in edematous dog lungs.  J. Appl. Physiol. 51:1268-1277, 1981.

 

30.       Taylor, A.E., J.C. Parker, P.R. Kvietys, and M. Perry.  Pulmonary interstitium in capillary exchange.  In: Mechanisms of Lung Microvascular Injury.  (Ed.) N.C. Staub and A. Malik, N.Y. Acad. Sci. 384:146-165, 1982.

 

31.       Taylor, A.E., J.C. Parker, and R.C. Allison.  Capillary exchange of fluid and protein.  In: Critical Care Vol. 3.  (Ed.) W.C. Shoemaker and W.L. Thompson.  Soc. Crit. Care, Fullerton, CA, pp. III B 1-26, 1982.

32.       Parker, J.C., and A.E. Taylor.  Comparison of capsular and intra-alveolar fluid pressures in the lung.  J. Appl. Physiol. 52:1444-1454, 1982.

 

33.       Martin, D.J., J.C. Parker, and A.E. Taylor.  Simultaneous comparison of tracheobronchial and right duct lymph dynamics in dogs.   J. Appl. Physiol. 54:199-207, 1983.

 

34.       Holloway, H.M. Perry, J. Downey, J.C. Parker, and A.E. Taylor.  Estimation of effective capillary pressure in intact lungs.  J. Appl. Physiol. 54:846-851, 1983.

 

35.       Parker, J.C., D. Martin, and A.E. Taylor.  Extravascular fluid compartmentation and lymph flow in edematous lungs.  In: Advances in Lympholosy.  (Ed.) V. Bartos and J.W. Davidson,

Avicenum, Czech., Medical Press, Prague, pp. 192-202, 1982.

                            

36.       Parker, J.C., P.R. Kvietys, K.P. Ryan, and A.E. Taylor.  Comparison of isogravimetric and venous occlusion pressures in isolated dog.  J. Appl. Physiol. 55:964-968, 1983.

 

37.       Parker, J.C., L. Campbell, S. Gilchrist, G. Longenecker, and A.E. Taylor.  Failure of myocardial ischemia to increase pulmonary microvascular permeability in dogs.  J. Appl. Physiol. 56:691-699, 1984.

 

38.       Taylor, A.E., D. Martin, and J.C. Parker.  The effects of oxygen radicals on pulmonary edema formation.  Surgery 94:433-438, 1983.

 

39.       Parker, J.C., D. Martin, G. Rutili, and A.E. Taylor.  Prevention of Free Radical Mediated Vascular Permeability Increases in Lung Using Superoxide Dismutase.  Chest 83:52S-54S, 1983.

 

40.       Rutili, G., J.C. Parker, and A.E. Taylor.  Fluid balance in ANTU-injured lungs during crystalloid and colloid infusions.  J. Appl. Physiol. 56:983-998, 1984.

 

41.       Perry, M.A., C.A. Navia, D.N. Granger, J.C. Parker, and A.E. Taylor.  Calculation of equivalent pore radii in dog hind paw capillaries using endogenous lymph and plasma proteins.  Microvasc. Res. 26:250-253, 1983.

 

42.       Allison, R.C., J.C. Parker, C.E. Duncan, and A.E. Taylor.  Effect of air embolism on the measurement of extravascular lung thermal volume.  J. Appl. Physiol.: Respirat. Environ. Exercise Physiol. 54(4):943-949, 1983.

 

43.       Martin, D., K. Rehder, J.C. Parker, and A.E. Taylor.  High-frequency ventilation: lymph protein flux, and lung water.  J. Appl. Physiol.: Respirat. Environ. Exercise Physiol. 57(1):240-245, 1984.

 

44.       Rippe, B., R.C. Allison, J.C. Parker, and A.E. Taylor.  Effects of histamine serotonin, and norepinephrine on circulation of dog lungs.  J. Appl. Physiol.: Respirat. Environ. Exercise Physiol. 57(1):223-232, 1984.

45.       Rippe, B., M. Townsley, J. Thigpen, J.C. Parker, R.J. Korthuis, and A.E. Taylor.  Effects of vascular pressure on the pulmonary microvasculature in isolated dog lungs.  J. Appl. Physiol.: Respirat. Environ. Exercise Physiol. 57(1):233-239, 1984.

 

46.       Parker, J.C., M.A. Perry, and A.E. Taylor.  Permeability of the microvascular barrier.  In: Edema.  Eds. N.C. Staub and A.E. Taylor.  Chap. 7.  Raven Press, New York, 1984, pp. 143-187.

 

47.       Parker, J.C., J. Ryan, and A.E. Taylor.  Plasma-lymph albumin kinetics, total lymph flow and tissue hematocrit in normally hydrated dog lungs.  Microvasc. Res. 28:254-269, 1984.

 

48.       Parker, J.C., M.I. Townsley, B. Rippe, and J. Thigpen.  Increased microvascular permeability in dog lungs due to high peak airway pressures.  J. Appl. Physiol. 57:1809-1816, 1984.

 

49.       Taylor, A.E., B. Rippe, M. Townsley, R. Korthuis, and J.C. Parker.  Interstitial lung tissue fluid resistance.  In: Frontiers in Physiology Research, ed., by D.G. Garlick and P.I. Korner.  Australian Academy of Science, pp. 120-161, 1984.

 

50.       Gilchrist, S.A., and J.C. Parker.  Exclusion of charged macromolecules in the pulmonary interstitium.  Microvasc. Res. 30:88-98, 1985.

 

51.       Taylor, A.E., and J.C. Parker.  The interstitial spaces in lymph flow.  In: Handbook of Physiology: Respiration, Vol. 4, A.P. Fishman and A.B. Fisher (eds.), Am. Physiol. Soc., Bethesda, MD 1985, pp. 167-320.

 

52.       Rippe, B., M. Townsley, J.C. Parker, and A.E. Taylor.  The osmotic reflection coefficient for total plasma protein in lung microvessels.  J. Appl. Physiol. 58:436-442, 1985.

 

53.       Parker, J.C., S. Gilchrist, and A.E. Taylor.  Plasma-lymph exchange and interstitial distribution volumes of charged macromolecules.  J. Appl. Physiol. 59:1128-1136, 1985.

 

54.       Parker, J.C., B. Rippe, and A.E. Taylor.  Fluid filtration and protein clearances through large and small pore populations in dog lung capillaries.  Microvas. Res. 31:1-17, 1986.

 

55.       Parker, J.C.  Transvascular clearance and distribution of charged macromolecules in ANTU lung injury.  J. Appl. Physiol. 60:1221-1229, 1986.

 

56.       Taylor, A.E., J.C. Parker, and B. Rippe.  Edema and the tissue resistance safety factor.  Chapter 9.  In: Tissue Nutrition and Viability, Ed. by A.R. Hargens.  Springer-Verlag, New York, NY, 1986. pp. 185-196.

 

57.       Rippe, B., J.C. Parker, M.I. Townsley, N.A. Mortillaro, and A.E. Taylor.  Segmental vascular resistances and compliances in dog lung.  J. Appl. Physiol. 62:1206-1215, 1987.

 

58.       Parker, J.C., M. Miniati, R. Pitt, and A.E. Taylor.  Interstitial distribution of charged macromolecules in the dog lung: A kinetic model.  Ann. Biomed. Eng. 15:157-172, 1987.

 

59.       Townsley, M.I., R.J. Korthuis, B. Rippe, J.C. Parker, and A.E. Taylor.  Validation of double vascular occlusion method for Pc,i in lung and skeletal muscle.  J. Appl. Physiol. 61:127-132, 1986.

 

60.       Pitt, R.M., J.C. Parker, G.J. Jurkovich, A.E. Taylor, and P.W. Curreri.  Analysis of altered capillary pressure and permeability after thermal injury.  J. Surg. Res. 42:693-702, 1987.

 

61.       Townsley, M.I., J.C. Parker, R.J. Korthuis, and A.E. Taylor.  Alterations in hemodynamics and Kf,c during lung mass resection.  J. Appl. Physiol. 63:2460-2466, 1987.

 

62.       Parker, J.C. Transport and distribution of charged macromolecules in lungs. Adv. Microcirc. 13:150-159, 1987.

 

63.       Miniati, M., J.C. Parker, M. Pistolesi, J. Cartledge, C. Giuntini, and A.E. Taylor.  Albumin reabsorption kinetics from the pleural spaces of dogs.  Am. J. Physiol. 255:H375-H385, 1988.

 

64.       Parker, J.C. Transvascular transport and distribution volumes of charged macromolecules in normal and injured lungs.  In: Interstitial Fluid Dynamics, ed. by N.C. Staub and A. Hargens.  S. Karger, Basel, 1988.

 

65.       Parker, J.C., M. Miniati, A.E. Taylor, and R. Pitt.  Pulmonary microvascular permeability of charged isozymes of lactate dehydrogenase (LDH) in isolated dog lungs.  In: M. Tsuchiya (Ed.) Microcirculation - An Update, Vol. 1 (1987).

 

66.       Taylor, A.E., J.C. Parker, R.C. Allison, and M. Perry.  Capillary exchange of fluid and protein.  In: Textbook of Critical Care, ed. by W. Shoemaker, W.L. Thompson, and P.R. Holbrook.  Saunders Publishing Co: Philadelphia, PA, 1988.

 

67.       Grimbert, F.A., D. Martin, J.C. Parker, and A.E. Taylor.  Pulmonary blood flow vs. microvascular pressure effects on lung lymph flow in dogs.  Am. J. Physiol. 255:H1149-H1155, 1988.

 

68.       Townsley, M.I., J.C. Parker, G.L. Longenecker, M.L. Perry, R.M. Pitt, and A.E. Taylor.  Pulmonary embolism: Analysis of endothelial pore sizes in canine lung.  Am. J. Physiol. 255:H1075-H1083, 1988.

 

69.       Taylor, A.E., K. Rehder, R. Hyatt, and J.C. Parker.  Clinical Pulmonary Physiology, Saunders Publishing Co: Philadelphia, PA, 1989.

 

70.       Cope, D.K., J.C. Parker, R.C. Allison, and A.E. Taylor.  The Gaar equation is not a reliable predictor of pulmonary capillary pressure.  Critical Care Medicine 17:300, 1989.

 

71.       Parker, J.C., M.I. Townsley, and J.T. Cartledge.  Edema increases transvascular filtration rate but not filtration coefficient in dog lungs.  J. Appl. Physiol. 66:1553-1560, 1989.

 

72.       Hernandez, L.A., K.J. Peevy, A.A. Moise, and J.C. Parker.  Chest wall restriction limits high airway pressure-induced lung injury in young rabbits.  J. Appl. Physiol. 66:2364-2368, 1989.

 

73.       Barman, Scott A., Jeffrey L. Ardell, J.C. Parker, Michele L. Perry, and A.E. Taylor.  Pulmonary and systemic blood flow contributions to upper airways in canine lung.  Am J. Physiol. 255 (Heart Circ. Physiol. 24): H1130-H1135, 1988.

 

74.       Allison, Ronald C., Bengt Rippe, V. Ravi Prasad, J.C. Parker, and A.E. Taylor.  Pulmonary vascular permeability and resistance measurements in control and ANTU-injured dog lungs.  Am. J. Physiol. 256 (Heart Circ. Physiol. 25): H1711-1718, 1989.

 

75.  Cope, D.K., J.C. Parker, M.D. Taylor, M. Houston, and A.E. Taylor.  Pulmonary capillary pressures during hypoxia and hypoxemia: Experimental and clinical studies.  Crit. Care Med. 17:853-857, 1989.

 

76.       Peevy, K.J., L.A. Hernandez, A.A. Moise, J.C. Parker.  Barotrauma and microvascular injury in lungs of non-adult rabbits: Effect of ventilation pattern.  Critical Care Medicine 18:634-637, 1990.

 

77.       Shibamoto, T., J.C. Parker, A.E. Taylor, and M.I. Townsley.  Derecruitment of filtration surface area in paraquat-injured isolated dog lungs.  J. Appl. Physiol. 68:1581-1589, 1990. 

 

78.       Shibamoto, T., A.E. Taylor, and J.C. Parker. PO2 modulation of paraquat-induced microvascular injury in isolated dog lungs.  J. Appl. Physiol. 68:2119-2127, 1990. 

 

79.       Parker, J.C., L.A. Hernandez, G.L. Longenecker, K. Peevy, and W. Johnson.  Lung edema due to high peak inspiration pressures in dogs: Role of increased microvascular filtration pressure and permeability.  Am. Rev. Respir. Dis. 142:321-328, 1990.

 

80.       Fujimoto, K., J.C. Parker, and S.G. Kayes.  Activated eosinophils increase vascular permeability and resistance in isolated perfused rat lungs.  Am. Rev. Respir. Dis. 142:1414-1421, 1990.

 

81.  Hernandez, L.A., P.J. Coker, S. May, A.L. Thompson, and J.C. Parker.  Mechanical ventilation increases microvascular permeability in oleic acid injured lungs.  J. Appl. Physiol. 69:2057-2061, 1990.

 

82.  Adkins, W.K., L.A. Hernandez, P.J. Coker, B. Buchanan, and J.C. Parker.  Age affects susceptibility to pulmonary barotrauma in rabbits.  Critical Care Medicine 19:390-393, 1991.

 

83.  Ishibashi, M., R.K. Reed, M.I. Townsley, J.C. Parker, and A.E. Taylor.  Albumin transport across pulmonary capillary interstitial barrier in anesthetized dogs.  J. Appl. Physiol. 70(5):2104-2110, 1991.

84.  Cope, D.K., R.C. Allison, J.N. Miller, J.C. Parker, and A.E. Taylor.  Estimation of pulmonary capillary pressure in intact dog lungs using the arterial occlusion technique [letter; comment].  Am. Rev. Respir. Dis. 141(6):1602-1603, 1990.

 

85.  Parker, J.C., D.K. Cope, and M.P. Houston.  Regional pulmonary vascular pressures and resistances during unilateral hypoxia.  [letter]  Crit. Care Med. 18:1493-1494, 1990.

 

86.  Parker, J.C., L.A. Hernandez, and K. Peevy.  What is the mechanism of pulmonary edema during high volume ventilation?  [letter, reply]  Am. Rev. Respir. Dis. 143:1198-1200, 1991.

 

87. Fujimoto, K., J.C. Parker, and S.G. Kayes.  O2 radical scavengers protect against eosinophil-induced injury in isolated perfused rat lungs. J. Appl. Physiol. 73:687-694,1992.

 

88. Shibamoto, T. and J.C. Parker.  Fructose 1,6-diphosphate augments paraquat injury in isolated dog lungs.  J. Appl. Physiol. 71(5):1830-36, 1991.

 

89. Parker, J.C., L.A. Hernandez, and K.J. Peevy. High Volume Stress Failure of Pulmonary Capillaries. In: High Altitude Medicine. Eds. G. Ueda, J.T. Reeves, and M. Sekiguchi. Shinshu Univ. Press, Matsumoto, Japan, pp.139-144,1992.

 

90. Coker, P.J., L.A. Hernandez, K.J. Peevy, W.K. Adkins, and J.C. Parker.  Increased sensitivity to mechanical ventilation in non-compliant young rabbit lungs. Crit. Care Med. 20:635-40,1992.

 

91. Shibamoto, T. and J.C.Parker. Effects of hyperoxia, hypoxia and fructose-1,6-diphosphate on paraquat induced pulmonary injury in isolated dog lungs. In: Pulmonary