CURRICULUM VITAE
James C. Parker
PERSONAL INFORMATION:
Current
Position Title: Professor
Professional
Address: University
of South Alabama
College
of Medicine
Department
of Physiology
MSB
3024
Mobile,
Alabama 36688
Citizenship: United
States
EDUCATION:
High School Education:
Metairie
County Day School, Metairie, Louisiana -1957.
Undergraduate Education:
B.S.
- Biology & Chemistry - Washington and Lee University, Lexington, VA -
1961.
Graduate Education:
Doctorate:
Ph.D. - Physiology - University of Mississippi, Graduate School of
Medical
Sciences, Jackson, Mississippi - 1972.
Honorary Awards:
Dean's
List; Honor Roll - Washington and Lee University.
Pharmacia
Travel Award of the Microcirculatory Society, 1981 - Funds for travel to
European
Research Laboratories.
Fellowship Awards:
Mississippi
Heart Association Research Fellowship, 1973-74.
NIH
Predoctoral Fellowship, Cardiovascular Physiology, University of Mississippi
Medical
Center, 1968-72.
Mayo
Research Foundation Fellowship, June-August 1963, Experimental Pathology.
PROFESSIONAL QUALIFICATIONS:
National
Committees and Offices:
NIH
CVA-AHR Cardiovascular and Pulmonary Study Section, Washington, D.C.,
February
13-15, 1979.
Awards
Committee, United States Microcirculatory Society, 1981-84, Chairman, 1983-84.
Research
Advisory Committee, Alabama Heart Association, 1983-86.
NIH
HLI Respiratory and Applied Physiology Study Section, Washington, D.C.,
1984
- 1987.
Editorial
Board, J. Appl. Physiol., 1984-93.
Reviewer;
American Journal of Respiratory and Critical Care Medicine,
Circulation
Research, Microvascular Research, American
Journal of Physiology,
Journal
of Applied. Physiology, Journal of
Physiology (Lond.),
Journal
of Clinical Investigation, Critical Care Medicine
NIH
Trauma and Burn Research Fellowship Review Committee, 1984.
NIH
NIGMS Site Visit Committee, 1986, 1987.
NIH
Program Project Review Site Visit, Seattle, WA, 1987.
NIH
Cancer Therapeutics Review Committee Site Visit, Richmond, VA., 1987.
NIH
ARDS SCOR Review Committee Site Visit, Seattle, WA, 1988.
NIH
NLS Review Committee Site Visit, San Francisco, CA, 1987.
NIH
Physiologic Sciences Study Section, Bethesda, MD March 1-3, 1995.
NIH
SBIR/STTR Study Section, Bethesda, MD 1999.
NIH
SBIR Study Section SSS-3, Chevy Chase, MD, Feb. 27-28, 2002
Am.
Heart Assoc. S. E. Region Peer Review Committee, Tampa, FL, April 7-9, 2002
NIH
NHLBI Program Project Review Committee, Bethesda, MD, May 8, 2002
NIH
Neuro SBIR ZRG1 BSCT 10 B study section, Bethesda, MD, Dec. 4, 2003
Gulf
Coast Physiologic Society. Treasurer. 2003-4.
NIH
NIGMS Trauma, burn and perioperative injury center study section. March 9-10,
2004
Professional Society Memberships:
American
Physiological Society
Circulation
and Respiratory Sections of American Physiological Society
Microcirculatory
Society
Sigma
Xi
Lung
Water Club
International
Lymphology Society
Alabama
Heart Association
American
Heart Association, Circulation Council
North
American Vascular Biology Organization
New
York Academy of Sciences
American
Thoracic Society
Past Professional Experience:
Associate
Professor, 1980-83, University of South Alabama, College of Medicine,
Department of Physiology,
Mobile, Alabama.
Assistant
Professor, 1977-80, University of South Alabama, College of Medicine,
Department
of Physiology, Mobile, Alabama.
Assistant
Professor, 1973-77, University of Mississippi Medical Center,
Department
of Physiology, Jackson, Mississippi.
Research
Associate, 1972-73, University of Mississippi Medical Center,
Department
of Physiology and Biophysics, Jackson, Mississippi.
ACADEMIC QUALIFICATIONS:
Present Appointment:
1983-Present
- Professor, Department of Physiology
Faculty Teaching Assignments:
Pulmonary
Physiology:
1979-Pres.-
COM I Medical Physiology course
1980-
Senior elective in Physiology
1985-Pres.-
Advanced Respiratory Physiology
1981-Pres.
- Advanced Cardiovascular Physiology
1984-
Pres. BEAR Physiology course for minority students.
1990-Pres.-Journal
Club
Hematology:
1978 - COM I Medical Physiology course
Student Laboratories:
1978-Pres.-
COM I Medical Physiology
1985-Pres.Intro.
to Laboratory Physiology
Committee Assignments:
USAMC
Research Advisory Committee, 1979-83
Graduate
Student Promotions Committee, 1982-85
USAMC
Medical School Admissions Committee, 1980-84, 1992-94 Ad Hoc
American
Heart Association, Alabama Afficliate Research Advisory Committee, 1982-86
North
American Microcirculatory Society Awards Committee, 1981-84; Chairman 1983-84
USAMC
Animal Health and Welfare Committee, 1984-87
USAMC
Radiation Safety Committee, 1984-87, 1996-1999
USAMC
Medical Student Summer Research Committee, 1983-87, Chairman, 1985-86
USAMC
Continuing Education Committee 1990-1991
USAMC
Committee on Ethics in Research 1991-1992
USAMC
Patent Committee 1993-1995, Chairman, 2003-5
USAMC
Faculty Committee on Appointments, Promotions, and Evaluations 1993-1995
USAMC
Biomedical Library Committee 1993-1995
USAMC
University Faculty Grievence Committee 1994-1997
USAMC
Curriculum Committee 1995-1998
Alabama
Regional Science Fair Judge 1992-1999
USAMC
Graduate recruiting committee 2003-4
Research Grants:
As
Principal Investigator:
NIH 2 R42
HL57040 - 02 Phase II STTR,“Airway perfusion
assisted liquid ventilator”, 7/1/01-6/31/03, $500,000, J.C. Parker, P.I.,
$250,000 annual
NIH 1 P01
HL66299 Project 2, J. C. Parker, P.I.., $220,000 annual, In: “Lung endothelial
cell phenotypes”, 12/01/01-11/31/06, $6,941,491, Troy Stevens, P.I.
NIH
1 R01 HL66347 “Mechanical Injury to Lung Endothelium,” 12/1/2000
-11/31/2005,
$1,244,615, J.C. Parker, P.I., $248,923 annual.
NIH
1 R41 HL57040-01A1 STTR, “Airway perfusion assisted liquid ventilator,”
2/1/99-1/30/00,
$105,000, J.C. Parker, P.I.
American
Heart Association, Southeast Affiliate, 98101 80SE,"Mechanical ventilation
induced lung injury,"7/1/98-
6/30/00, $70,000,
J.C.Parker,P.I. American Heart
Association, #94013094, "Heterogeneity of
pulmonary blood flow and injury".
7/1/94-6/30/97, $136,000, J.C.Parker, P.I.
American
Heart Association, #91011060, "Eosinophil and neutrophil effects
on
microvascular permeability in the lung,"7/1/91-6/30/94,$74,272,
J.C.Parker,
P.I.
American
Heart Association, Alabama Affiliate, AL-G-920030,"Tracheal blood
flow
during high frequency Jet Ventilation,"7/1/92-6/30/93,
$25,000,
J.C.Parker,P.I.
NIH
1 RO1 HL37341, "Lung Microvascular Injury due to Airway Pressure",
4/1/87-3/31/90,
$197,271
NIH
2 RO1 HL24571, "Interstitial Fluid Pressure and Excluded Volume in the
Lung";
8/1/79-7/31/82, $186,268; Renewal 8/1/82-7/31/87, $316,000;
Renewal
8/1/87-7/31/92, $526,000; J.C. Parker
P.I.
American
Lung Association, "Interstitial Pressure and Excluded Volume in
the
Lung", 6/1/79-5/30/81, $25,666.
American Heart Association,
"Interstitial Pressure and Excluded Volume in
the
Lung", 7/1/79-6/30/82, $61,820.
Intramural
- University of South Alabama, 2/15/78-2/15/79, "Pulmonary Capillary
and
Interstitial Protein Transport", $5,000.
Mississippi
Heart Association, "Dynamics of Pulmonary Vascular and Extravascular
Forces", 6/1/77-5/31/79,
$18,974 (not transferred).
Mississippi
Heart Association, "Energy Metabolism in
the
Ischemic Myocardium", 6/1/75-5/31/77, $16,780.
As
Co-Investigator:
NIH R01
HL67461-01.,”Tlymphocyte role in lung ischemia - reperfusion injury.”,
4/1/01-2/28/05, $200,000/yr., (A. E. Taylor, P.I.; J.C. Parker, 20% effort).
NIH R01
HL63302-01A2 “Airway submucosal glands and cystic fibrosis disease”
4/1/01-3/31/06, $1,486,263 (Stephen T. Ballard, P.I.; J.C. Parker, 5% effort)
NIH 1 P01
HL66299 Project 2, J. C. Parker, P.I.., $220,000 annual, In: “Lung endothelial
cell phenotypes”, 12/01/01-11/31/06, $6,941,491, Troy Stevens, P.I.
American
Lung Association, "Diaphragmatic function during
mechanical
ventilation in ewes.", $50,000 (Max Ferrigno,
P.I.,
7/1/95-6/30/97; J.C. Parker, 15%).
American
Heart Association, Alabama Affiliate, "Nitric Oxide
Modulation
of Oleic Acid Injured Lungs,"7/1/95-6/30/97,
$55,450,
(Michael M. Zayek, P.I; J.C.Parker, 10% effort. NIH, "Transport Across
Alveolar
Capillary
Membrane", 9/1/77-8/31/82, $200,715;
renewal
9/1/81-8/31/87, $545,000 (A.E. Taylor, P.I.).
(Renewal
9/1/87-8/31/92,
$640,000; J.C. Parker, 15%).
Parker
B. Francis Foundation Fellowship, 9/1/78-8/31/81, $72,000; renewal
9/1/81-8/31/83,
$72,000 (A.E. Taylor, P.I.).
American
Lung Association, "Barotrauma and Microvascular Injury in the
Immature
Lung", $35,000 (Alicia Moise,P.I., 7/1/88-6/30/90;
J.C.
Parker, 15%).
Patents Awarded: U. S. Patent No. 5,706,830
awarded on Jan. 13, 1998, entitled “Liquid ventilator
and use thereof ”, to J.C. Parker, ref. No.
87647.97R243.
Ph.D
Dissertation Committees
Michelle Lynn Perry 1988
William
Keith Adkins 1991
Peter S. Wilson 1993
Laura Trout 2001
Judy
Creighton
Donna
Cioffi
Diego
Alverez
Sarah
Sayner
Brad
Swiger
Post-Doctoral
Students
Roger
M. Pitt M.D.
Lucretia
A. Hernandez M.D., Ph.D.
Toshishiga
Shibamoto M.D., Ph.D.
Keisaku
Fujimoto M.D.,Ph.D.
Sawako
Yoshikawa M.D.,Ph.D.
Mircea
Anghelescu M.D.
Siobhan
Tarpey Ph.D.
Tokashige
Miyahara M.D., Ph.D.
Medical
Student Honors Program
Jarrod
Adkison B.Ch.E.
PUBLICATIONS:
TEXTBOOKS:
1. Taylor,
A.E., K. Rehder, R. Hyatt, and J.C. Parker.
Clinical Pulmonary Physiology, Saunders Publishing Co: Philadelphia, PA,
1989.
SCIENTIFIC PAPERS AND CHAPTERS:
1. Jones,
C.E., J.C. Parker, and E.E. Smith.
Determination of myocardial acid soluble adenine nucleotides on anion
exchange thin layers. J. Chromatography 64:378-344, 1972.
2. Parker,
J.C., and E.E. Smith. Effects of
xanthine oxidase inhibition in cardiac arrest.
Surgery 71:339-344, 1972.
3. Parker,
J.C., C.E. Jones, and E.E. Smith.
Determination of acid soluble nucleosides and bases in myocardium by
thin layer methods. J.
Chromatography 79:360-363, 1973.
4. Guyton,
A.C., A.E. Taylor, R.E. Drake, and J.C. Parker. Dynamics of subatmospheric pressure in pulmonary interstitial
fluid.
In: Lung Liquids, a CIBA Foundation Symposium. Elsevier, Amsterdam, 1976.
5. Parker,
J.C., C.E. Jones, and J.X. Thomas, Jr.
Effect of ischemia and infarction on regional content of adenine
nucleotides and derivatives in canine left ventricle. Cardiology 61:279-288, 1976.
6. Parker,
J.C., E.E. Smith, and C.E. Jones. The
role of nucleoside and nucleobase metabolism in myocardial adenine nucleotide
regeneration after cardiac arrest. Circulatory
Shock 3(1):11-20, 1976.
7. Jones,
C.E., J.X. Thomas, J.C. Parker, and R.E. Parker. Acute changes in adenine nucleotides, nucleotide derivaties and
contractile force in ischemic and non-ischemic and canine myocardium following
coronary occlusion. Cardiovascular
Research 10:275-282, 1976.
8. Parker,
J.C., and D.H. Pearce. Computation of
indicator dilution flows and transit times with a pocket calculator. Am. Heart J. 91:826-827, 1976.
9. Parker,
J.C., C.E. Jones, J.X. Thomas, and H.J. Granger. A dynamic analysis of energy and contractility transients in
ischemic myocardium. Proceedings of
Summer Computer Simulation Conference, pp. 539-544, 1977.
10. Parker,
J.C., A.C. Guyton, and A.E. Taylor.
Pulmonary transcapillary exchange and pulmonary edema. In: A.C. Guyton (ed.) International
Review of Physiology, Cardiovascular Physiology III. University Park Press, Baltimore, 1978.
11. Parker,
J.C., A.C. Guyton, and A.E. Taylor.
Pulmonary interstitial and capillary pressures estimated from
intra-alveolar fluid pressures. J. Appl. Physiology 44:267-276, 1978.
12. Guyton,
A.C., J.C. Parker, A.E. Taylor, T.E. Jackson, and D.S. Moffatt. Forces governing water movement in the
lung. In: Pulmonary edema. A.P. Fishman and E.M. Renkin, eds., Am.
Physiological Society, Bethesda, MD, 1979.
13. Parker,
J.C., and A.E. Taylor. Pulmonary
interstitial and capillary pressures estimated from intra-alveolar fluid
pressures (Letter), J. Appl. Physiol. 47-643-644, 1979.
14. Parker,
J.C., A.E. Taylor, R.E. Parker, and D.N. Granger. Vertical gradient in regional vascular resistance and pre- to
post-capillary resistance ratios in the dog lung. Lymphology 12:191-200, 1979.
15. Parker,
J.C., J.H. Falgout, R.E. Parker, D.N. Granger, and A.E. Taylor. The effect of volume loading on interstitial
albumin exclusion and lymph flow in the lung.
Circ. Res. 45:440-450, 1979.
16. Granger,
D.N., T. Miller, R.E. Allen, R.E. Parker, J.C. Parker, and A.E. Taylor. Permselectivity of the cat blood-lymph
barrier to endogenous macromolecules. Gastroenterology
77:103-109, 1979.
17. Granger,
D.N., N.A. Mortillaro, P.R. Kvietys, G. Rutili, J.C. Parker, and A.E.
Taylor. Role of the interstitial matrix
during intestinal volume absorption. Am.
J. Physiol. 238:G183-G189, 1980.
18. Parker,
J.C., R.E. Parker, D.N. Granger, and A.E. Taylor. Vascular permeability and transvascular fluid and proteins
transport in the dog lung. Circ. Res.
48:549-561, 1981.
19. Parker,
J.C., H.J. Falgout, F.A. Grimbert, and A.E. Taylor. The effect of increased vascular pressure on albumin excluded
volume and lymph flow in the dog lymph.
Circ. Res. 47:866-875, 1980.
20. Taylor,
A.E., J.C. Parker, D.N. Granger, and G. Rutili. Pulmonary edema: Changes in Starling Forces and Lymph Flow. In: Tissue Fluid Pressure and Composition. (Ed.) Alan Hargens, Williams and Wilkins
Co., pp. 135-143, 1981.
21. Perry,
M.A., and J.C. Parker. Indicator
measurement of splanchnic blood flow.
In: Measurement of Blood Flow.
(Eds.) D.N. Granger and G.B. Bulkley, Williams and Wilkins Co., pp.
159-176, 1981.
22. Parker,
J.C., F. Grimbert, G. Rutili, and A.E. Taylor.
Pulmonary lymph plasma oncotic pressure gradients after hemodilution,
increased vascular pressures, and albumin infusion. In: Recent Advances in Microcirculatory Research (Ed.) P.
Gaethtgens, S. Karger, Basel, pp. 251-254, 1981.
23. Taylor,
A.E., J.C. Parker, D.N. Granger, N.A. Motrillaro, and G.Rutili. Assessment of capillary permeability using
lymphatic protein flux: Estimation of the osmotic reflection coefficient. In: The Microcirculation, (Ed.) R. Effros,
H. Schmid-Schonbein, and J. Ditzel, Academic Press, pp. 19-32, 1981.
24. Parker,
J.C., R.C. Allison, and A.E. Taylor.
Edema affects intralveolar fluid pressures and interdependence in dog
lungs. J. Appl. Physiol.
51:911-921, 1981.
25. Grimbert,
F.A., J.C. Parker, and A.E. Taylor.
Increased pulmonary vascular permeability following acid aspiration. J.
Appl. Physiol. 51:335-345, 1981.
26. Kinnebrew,
P.S., J.C. Parker, J.J. Falgout, and A.E. Taylor. Pulmonary microvascular permeability following E. coli
endotoxin and hemorrhage. J. Appl.
Physiol. 52:403-409, 1982.
27. Rutili,
G., P. Kvietys, J.C. Parker, and A.E. Taylor.
Increased microvascular permeability induced by ANTU. J. Appl. Physiol. 52:1316-1323, 1982.
28. Rutili,
G., D.N. Granger, A.E. Taylor, J.C. Parker, and N.A. Mortillaro. Analysis of lymphatic protein data IV. Comparison of the different methods used to
estimate reflection coefficients and permeability-surface area products. Microvasc. Res. 23:347-360, 1982.
29. Parker,
J.C., M. Crain, F. Grimbert, G. Rutili, and A.E. Taylor. Total lung lymph flow and fluid
compartmentation in edematous dog lungs.
J. Appl. Physiol. 51:1268-1277, 1981.
30. Taylor,
A.E., J.C. Parker, P.R. Kvietys, and M. Perry.
Pulmonary interstitium in capillary exchange. In: Mechanisms of Lung Microvascular Injury. (Ed.) N.C. Staub and A. Malik, N.Y. Acad.
Sci. 384:146-165, 1982.
31. Taylor,
A.E., J.C. Parker, and R.C. Allison.
Capillary exchange of fluid and protein. In: Critical Care Vol. 3.
(Ed.) W.C. Shoemaker and W.L. Thompson.
Soc. Crit. Care, Fullerton, CA, pp. III B 1-26, 1982.
32. Parker,
J.C., and A.E. Taylor. Comparison of
capsular and intra-alveolar fluid pressures in the lung. J. Appl. Physiol. 52:1444-1454, 1982.
33. Martin,
D.J., J.C. Parker, and A.E. Taylor.
Simultaneous comparison of tracheobronchial and right duct lymph
dynamics in dogs. J. Appl. Physiol. 54:199-207, 1983.
34. Holloway,
H.M. Perry, J. Downey, J.C. Parker, and A.E. Taylor. Estimation of effective capillary pressure in intact lungs. J. Appl. Physiol. 54:846-851, 1983.
35. Parker,
J.C., D. Martin, and A.E. Taylor.
Extravascular fluid compartmentation and lymph flow in edematous
lungs. In: Advances in Lympholosy. (Ed.) V. Bartos and J.W. Davidson,
Avicenum, Czech., Medical Press, Prague, pp.
192-202, 1982.
36. Parker,
J.C., P.R. Kvietys, K.P. Ryan, and A.E. Taylor. Comparison of isogravimetric and venous occlusion pressures in
isolated dog. J. Appl. Physiol.
55:964-968, 1983.
37. Parker,
J.C., L. Campbell, S. Gilchrist, G. Longenecker, and A.E. Taylor. Failure of myocardial ischemia to increase
pulmonary microvascular permeability in dogs.
J. Appl. Physiol. 56:691-699, 1984.
38. Taylor,
A.E., D. Martin, and J.C. Parker. The
effects of oxygen radicals on pulmonary edema formation. Surgery 94:433-438, 1983.
39. Parker,
J.C., D. Martin, G. Rutili, and A.E. Taylor.
Prevention of Free Radical Mediated Vascular Permeability Increases in
Lung Using Superoxide Dismutase. Chest
83:52S-54S, 1983.
40. Rutili,
G., J.C. Parker, and A.E. Taylor. Fluid
balance in ANTU-injured lungs during crystalloid and colloid infusions. J. Appl. Physiol. 56:983-998, 1984.
41. Perry,
M.A., C.A. Navia, D.N. Granger, J.C. Parker, and A.E. Taylor. Calculation of equivalent pore radii in dog
hind paw capillaries using endogenous lymph and plasma proteins. Microvasc. Res. 26:250-253, 1983.
42. Allison,
R.C., J.C. Parker, C.E. Duncan, and A.E. Taylor. Effect of air embolism on the measurement of extravascular lung
thermal volume. J. Appl. Physiol.:
Respirat. Environ. Exercise Physiol. 54(4):943-949, 1983.
43. Martin,
D., K. Rehder, J.C. Parker, and A.E. Taylor.
High-frequency ventilation: lymph protein flux, and lung water. J. Appl. Physiol.: Respirat. Environ.
Exercise Physiol. 57(1):240-245, 1984.
44. Rippe,
B., R.C. Allison, J.C. Parker, and A.E. Taylor. Effects of histamine serotonin, and norepinephrine on circulation
of dog lungs. J. Appl. Physiol.:
Respirat. Environ. Exercise Physiol. 57(1):223-232, 1984.
45. Rippe,
B., M. Townsley, J. Thigpen, J.C. Parker, R.J. Korthuis, and A.E. Taylor. Effects of vascular pressure on the
pulmonary microvasculature in isolated dog lungs. J. Appl. Physiol.: Respirat. Environ. Exercise Physiol.
57(1):233-239, 1984.
46. Parker,
J.C., M.A. Perry, and A.E. Taylor.
Permeability of the microvascular barrier. In: Edema. Eds.
N.C. Staub and A.E. Taylor. Chap.
7. Raven Press, New York, 1984, pp.
143-187.
47. Parker,
J.C., J. Ryan, and A.E. Taylor. Plasma-lymph
albumin kinetics, total lymph flow and tissue hematocrit in normally hydrated
dog lungs. Microvasc. Res.
28:254-269, 1984.
48. Parker,
J.C., M.I. Townsley, B. Rippe, and J. Thigpen.
Increased microvascular permeability in dog lungs due to high peak
airway pressures. J. Appl. Physiol.
57:1809-1816, 1984.
49. Taylor,
A.E., B. Rippe, M. Townsley, R. Korthuis, and J.C. Parker. Interstitial lung tissue fluid
resistance. In: Frontiers in
Physiology Research, ed., by D.G. Garlick and P.I. Korner. Australian Academy of Science, pp. 120-161,
1984.
50. Gilchrist,
S.A., and J.C. Parker. Exclusion of
charged macromolecules in the pulmonary interstitium. Microvasc. Res. 30:88-98, 1985.
51. Taylor,
A.E., and J.C. Parker. The interstitial
spaces in lymph flow. In: Handbook
of Physiology: Respiration, Vol. 4, A.P. Fishman and A.B. Fisher (eds.),
Am. Physiol. Soc., Bethesda, MD 1985, pp. 167-320.
52. Rippe,
B., M. Townsley, J.C. Parker, and A.E. Taylor.
The osmotic reflection coefficient for total plasma protein in lung
microvessels. J. Appl. Physiol.
58:436-442, 1985.
53. Parker,
J.C., S. Gilchrist, and A.E. Taylor.
Plasma-lymph exchange and interstitial distribution volumes of charged
macromolecules. J. Appl. Physiol.
59:1128-1136, 1985.
54. Parker,
J.C., B. Rippe, and A.E. Taylor. Fluid
filtration and protein clearances through large and small pore populations in
dog lung capillaries. Microvas. Res.
31:1-17, 1986.
55. Parker,
J.C. Transvascular clearance and distribution
of charged macromolecules in ANTU lung injury.
J. Appl. Physiol. 60:1221-1229, 1986.
56. Taylor,
A.E., J.C. Parker, and B. Rippe. Edema
and the tissue resistance safety factor.
Chapter 9. In: Tissue
Nutrition and Viability, Ed. by A.R. Hargens. Springer-Verlag, New York, NY, 1986. pp. 185-196.
57. Rippe,
B., J.C. Parker, M.I. Townsley, N.A. Mortillaro, and A.E. Taylor. Segmental vascular resistances and
compliances in dog lung. J. Appl.
Physiol. 62:1206-1215, 1987.
58. Parker,
J.C., M. Miniati, R. Pitt, and A.E. Taylor.
Interstitial distribution of charged macromolecules in the dog lung: A
kinetic model. Ann. Biomed. Eng.
15:157-172, 1987.
59. Townsley,
M.I., R.J. Korthuis, B. Rippe, J.C. Parker, and A.E. Taylor. Validation of double vascular occlusion
method for Pc,i in lung and skeletal muscle.
J. Appl. Physiol. 61:127-132, 1986.
60. Pitt,
R.M., J.C. Parker, G.J. Jurkovich, A.E. Taylor, and P.W. Curreri. Analysis of altered capillary pressure and
permeability after thermal injury. J.
Surg. Res. 42:693-702, 1987.
61. Townsley,
M.I., J.C. Parker, R.J. Korthuis, and A.E. Taylor. Alterations in hemodynamics and Kf,c during lung mass
resection. J. Appl. Physiol.
63:2460-2466, 1987.
62. Parker,
J.C. Transport and distribution of charged macromolecules in lungs. Adv.
Microcirc. 13:150-159, 1987.
63. Miniati,
M., J.C. Parker, M. Pistolesi, J. Cartledge, C. Giuntini, and A.E. Taylor. Albumin reabsorption kinetics from the
pleural spaces of dogs. Am. J.
Physiol. 255:H375-H385, 1988.
64. Parker,
J.C. Transvascular transport and distribution volumes of charged macromolecules
in normal and injured lungs. In: Interstitial
Fluid Dynamics, ed. by N.C. Staub and A. Hargens. S. Karger, Basel, 1988.
65. Parker,
J.C., M. Miniati, A.E. Taylor, and R. Pitt.
Pulmonary microvascular permeability of charged isozymes of lactate
dehydrogenase (LDH) in isolated dog lungs.
In: M. Tsuchiya (Ed.) Microcirculation - An Update, Vol. 1
(1987).
66. Taylor,
A.E., J.C. Parker, R.C. Allison, and M. Perry.
Capillary exchange of fluid and protein. In: Textbook of Critical Care, ed. by W. Shoemaker, W.L.
Thompson, and P.R. Holbrook. Saunders
Publishing Co: Philadelphia, PA, 1988.
67. Grimbert,
F.A., D. Martin, J.C. Parker, and A.E. Taylor.
Pulmonary blood flow vs. microvascular pressure effects on lung lymph
flow in dogs. Am. J. Physiol.
255:H1149-H1155, 1988.
68. Townsley,
M.I., J.C. Parker, G.L. Longenecker, M.L. Perry, R.M. Pitt, and A.E.
Taylor. Pulmonary embolism: Analysis of
endothelial pore sizes in canine lung. Am.
J. Physiol. 255:H1075-H1083, 1988.
69. Taylor,
A.E., K. Rehder, R. Hyatt, and J.C. Parker.
Clinical Pulmonary Physiology, Saunders Publishing Co: Philadelphia, PA,
1989.
70. Cope,
D.K., J.C. Parker, R.C. Allison, and A.E. Taylor. The Gaar equation is not a reliable predictor of pulmonary
capillary pressure. Critical Care
Medicine 17:300, 1989.
71. Parker,
J.C., M.I. Townsley, and J.T. Cartledge.
Edema increases transvascular filtration rate but not filtration coefficient
in dog lungs. J. Appl. Physiol.
66:1553-1560, 1989.
72. Hernandez,
L.A., K.J. Peevy, A.A. Moise, and J.C. Parker.
Chest wall restriction limits high airway pressure-induced lung injury
in young rabbits. J. Appl. Physiol.
66:2364-2368, 1989.
73. Barman,
Scott A., Jeffrey L. Ardell, J.C. Parker, Michele L. Perry, and A.E.
Taylor. Pulmonary and systemic blood
flow contributions to upper airways in canine lung. Am J. Physiol. 255 (Heart Circ. Physiol. 24): H1130-H1135,
1988.
74. Allison,
Ronald C., Bengt Rippe, V. Ravi Prasad, J.C. Parker, and A.E. Taylor. Pulmonary vascular permeability and
resistance measurements in control and ANTU-injured dog lungs. Am. J. Physiol. 256 (Heart Circ.
Physiol. 25): H1711-1718, 1989.
75.
Cope, D.K., J.C. Parker, M.D. Taylor, M. Houston, and A.E. Taylor. Pulmonary capillary pressures during hypoxia
and hypoxemia: Experimental and clinical studies. Crit. Care Med. 17:853-857, 1989.
76. Peevy,
K.J., L.A. Hernandez, A.A. Moise, J.C. Parker.
Barotrauma and microvascular injury in lungs of non-adult rabbits:
Effect of ventilation pattern. Critical
Care Medicine 18:634-637, 1990.
77. Shibamoto,
T., J.C. Parker, A.E. Taylor, and M.I. Townsley. Derecruitment of filtration surface area in paraquat-injured isolated
dog lungs. J. Appl. Physiol.
68:1581-1589, 1990.
78. Shibamoto,
T., A.E. Taylor, and J.C. Parker. PO2 modulation of paraquat-induced
microvascular injury in isolated dog lungs.
J. Appl. Physiol. 68:2119-2127, 1990.
79. Parker,
J.C., L.A. Hernandez, G.L. Longenecker, K. Peevy, and W. Johnson. Lung edema due to high peak inspiration
pressures in dogs: Role of increased microvascular filtration pressure and
permeability. Am. Rev. Respir. Dis.
142:321-328, 1990.
80. Fujimoto,
K., J.C. Parker, and S.G. Kayes.
Activated eosinophils increase vascular permeability and resistance in
isolated perfused rat lungs. Am.
Rev. Respir. Dis. 142:1414-1421, 1990.
81.
Hernandez, L.A., P.J. Coker, S. May, A.L. Thompson, and J.C.
Parker. Mechanical ventilation
increases microvascular permeability in oleic acid injured lungs. J. Appl. Physiol. 69:2057-2061, 1990.
82.
Adkins, W.K., L.A. Hernandez, P.J. Coker, B. Buchanan, and J.C.
Parker. Age affects susceptibility to
pulmonary barotrauma in rabbits. Critical
Care Medicine 19:390-393, 1991.
83.
Ishibashi, M., R.K. Reed, M.I. Townsley, J.C. Parker, and A.E.
Taylor. Albumin transport across
pulmonary capillary interstitial barrier in anesthetized dogs. J. Appl. Physiol. 70(5):2104-2110,
1991.
84. Cope,
D.K., R.C. Allison, J.N. Miller, J.C. Parker, and A.E. Taylor. Estimation of pulmonary capillary pressure
in intact dog lungs using the arterial occlusion technique [letter; comment]. Am. Rev. Respir. Dis.
141(6):1602-1603, 1990.
85.
Parker, J.C., D.K. Cope, and M.P. Houston. Regional pulmonary vascular pressures and resistances during
unilateral hypoxia. [letter] Crit. Care Med. 18:1493-1494, 1990.
86.
Parker, J.C., L.A. Hernandez, and K. Peevy. What is the mechanism of pulmonary edema during high volume
ventilation? [letter, reply] Am. Rev. Respir. Dis. 143:1198-1200,
1991.
87. Fujimoto, K., J.C. Parker, and S.G.
Kayes. O2 radical scavengers
protect against eosinophil-induced injury in isolated perfused rat lungs. J.
Appl. Physiol. 73:687-694,1992.
88. Shibamoto, T. and J.C. Parker. Fructose 1,6-diphosphate augments paraquat
injury in isolated dog lungs. J.
Appl. Physiol. 71(5):1830-36, 1991.
89. Parker, J.C., L.A. Hernandez, and K.J.
Peevy. High Volume Stress Failure of Pulmonary Capillaries. In: High
Altitude Medicine. Eds. G. Ueda, J.T. Reeves, and M. Sekiguchi. Shinshu
Univ. Press, Matsumoto, Japan, pp.139-144,1992.
90. Coker, P.J., L.A. Hernandez, K.J. Peevy,
W.K. Adkins, and J.C. Parker. Increased
sensitivity to mechanical ventilation in non-compliant young rabbit lungs. Crit.
Care Med. 20:635-40,1992.
91. Shibamoto, T. and J.C.Parker. Effects of hyperoxia, hypoxia and fructose-1,6-diphosphate on paraquat induced pulmonary injury in isolated dog lungs. In: Pulmonary