Research Interests:
The research in my laboratory is concerned
with a condition which occurs when an organ
has poor or no blood flow for a few minutes
(ischemia) and then blood flow is returned to
the organ (reperfusion). The result of this
procedure is termed ischemia/reperfusion
(I/R) and causes extensive damage to the
cells lining the small blood vessels and the
cells in the organ. These studies are
conducted in the lung and involve evaluating
the different lymphocytes and the substances
they release during I/R. The procedure causes
an extensive activation of the inflammatory
response. We also evaluate the different
inflammatory mediators released in I/R and
determine how different interventions can
modulate or enhance the lung damage
associated with this model of inflammation.
Recent Publications:
1. Moore, T.M., P.H. Khimenko, W.K. Adkins
and A.E. Taylor. Leukocyte and endothelial
cell adhesion molecules contribute to
ischemia and reperfusion-induced injury in
the isolated rat lung. J. Appl. Physiol.
78: 2245-2252, 1995.
2. Moore, T.M., P.L. Khimenko and A.E.
Taylor. Restoration of normal pH triggers
ischemia-reperfusion injury in lung by Na/H
exhange activation. Am. J. Physiol. 269:
H1501-H1505, 1995.
3. Reeves, J.T. and A.E. Taylor. Pulmonary
hemodynamics and fluid exchange in the lung
during exercise. In: Handbook of
Physiology: Integration of Motor;
Circulatory, Respiratory , and Metabolic
Control During Excercise, L.B. Rowell and
J.T. Shepherd, Chapter 13, 585-613, 1996.
4. Taylor, A.E. Microvascular fluid and
solute exchange. In: Encyclopedia of Human
Biology. Volume 5, 687-700, 1997.
5. Taylor, A.E., P.L. Khimenko, T.M. Moore
and W.K. Adkins. Fluid Balance. In: The
Lung. R.G. Crystal, J.B. West, et al
(Eds.), Chapter 13, 2nd edition, 1549-1566,
1997.
Mailing Address:
Department of Physiology
Room 3074 Medical Sciences Building
University of South Alabama
College of Medicine
Mobile, Alabama 36688
Phone: 251-460-6394
FAX: 251-460-6464
Click here for Dr. Aubrey E. Taylor's
complete Curriculum Vitae
